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镁柠檬酸在胶囊内镜检查前准备中的效果:一项随机、前瞻性、开放标签、组间试验。

Effectiveness of magnesium citrate as preparation for capsule endoscopy: a randomized, prospective, open-label, inter-group trial.

机构信息

Department of Gastroenterology, Fukuoka University Chikushi Hospital, Chikushino City, Japan.

出版信息

Digestion. 2012;86(1):27-33. doi: 10.1159/000337937. Epub 2012 Jun 15.

DOI:10.1159/000337937
PMID:22710397
Abstract

BACKGROUND AND AIM

Capsule endoscopy (CE) is effective in the detection of small bowel lesions. Many studies have been conducted on the effectiveness of preparations in improving diagnostic yield, but an effective method has yet to be confirmed. We used magnesium citrate as preparation for CE and evaluated its effectiveness.

METHODS

50 patients who underwent CE were randomly allocated to two groups - group A (preparation provided) and group B (no preparation). Group A were administered 34 g of magnesium citrate at 8 p.m. the night before the examination. Group B were not administered a laxative.

RESULTS

The cleansing efficacy score was 24.4 ± 4.4 points for group A and 22.9 ± 4.4 points for group B, with no significant difference between groups. No significant difference was seen in the large bowel arrival rate between groups: 14 cases (63.6%) for group A and 16 cases (72.7%) for group B.

CONCLUSION

In this study, superiority was not seen for cleansing efficacy, large bowel arrival rate for the preparation method involving administration of hypertonic MC solution 12 h prior to the procedure.

摘要

背景与目的

胶囊内镜(CE)在小肠病变的检测中具有较高的检出率。已有大量研究针对提高诊断率的准备方法进行了评估,但尚未确定有效的方法。本研究采用柠檬酸镁作为 CE 的准备方法,并对其有效性进行评估。

方法

将 50 例行 CE 的患者随机分为两组:A 组(提供准备)和 B 组(无准备)。A 组于检查前一天晚上 8 点服用 34g 柠檬酸镁。B 组未给予泻药。

结果

A 组的肠道清洁评分(CE)为 24.4±4.4 分,B 组为 22.9±4.4 分,两组间无显著差异。两组间大肠到达率无显著差异:A 组 14 例(63.6%),B 组 16 例(72.7%)。

结论

在这项研究中,与检查前 12 小时给予高渗 MC 溶液的准备方法相比,在肠道清洁效果和大肠到达率方面,该方法没有优势。

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