运动消褪的不同参照系：双重分离。
Motor extinction in distinct reference frames: a double dissociation.
机构信息
Department of Neurology, Johns Hopkins University, School of Medicine, Baltimore, MD, USA.
出版信息
Behav Neurol. 2013;26(1-2):111-9. doi: 10.3233/BEN-2012-110254.
OBJECTIVE
Test the hypothesis that right hemisphere stroke can cause extinction of left hand movements or movements of either hand held in left space, when both are used simultaneously, possibly depending on lesion site.
METHODS
93 non-hemiplegic patients with acute right hemisphere stroke were tested for motor extinction by pressing a counter rapidly for one minute with the right hand, left hand, or both simultaneously with their hands held at their sides, or crossed over midline.
RESULTS
We identified two distinct types of motor extinction in separate patients; 20 patients extinguished left hand movements held in left or right space (left canonical body extinction); the most significantly associated voxel cluster of ischemic tissue was in the right temporal white matter. Seven patients extinguished either hand held in left space (left space extinction), and the most significantly associated voxel cluster of ischemic tissue was in right parietal white matter.
CONCLUSIONS
There was a double dissociation between left canonical body extinction and left space motor extinction. Left canonical body extinction seems to be associated with more dorsal (parietal) ischemia, and left canonical body extinction seems to be associated with more ventral (temporal) ischemia.
目的
检验假设，即右半球卒中可能导致左手或双手同时置于左侧空间时的运动消失，具体取决于病变部位。
方法
对 93 例非偏瘫的急性右半球卒中患者进行运动消消失测试，方法是用右手、左手或双手同时快速按压计数器一分钟，双手置于身体两侧或中线交叉。
结果
我们在不同患者中发现了两种不同类型的运动消失；20 例患者在左侧或右侧空间（左侧经典性身体消失）时，左手运动消失；与缺血组织最显著相关的体素簇位于右侧颞叶白质。7 例患者在左侧空间（左侧空间消失）时，一只手或双手运动消失，与缺血组织最显著相关的体素簇位于右侧顶叶白质。
结论
左侧经典性身体消失和左侧空间运动消失之间存在双重分离。左侧经典性身体消失似乎与更背侧（顶叶）缺血有关，而左侧经典性身体消失似乎与更腹侧（颞叶）缺血有关。
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