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鲁文佐里山脉的急性肺水肿。

Acute pulmonary oedema on the Ruwenzori mountain range.

作者信息

Naeije R, Mélot C

机构信息

Laboratory of Cardiovascular and Respiratory Physiology, Erasmus University Hospital, Brussels, Belgium.

出版信息

Br Heart J. 1990 Dec;64(6):400-2. doi: 10.1136/hrt.64.6.400.

DOI:10.1136/hrt.64.6.400
PMID:2271350
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1224820/
Abstract

A 40 year old man had an episode of severe pulmonary oedema at 4000-5000 m during the ascent of the Margherita peak (5109 m) of Mount Stanley on the Ruwenzori. He had taken acetazolamide and high dose dexamethasone to treat symptoms of acute mountain sickness. Six years before he had been studied by right heart catheterisation as a healthy volunteer during hypoxic breathing at sea level. His pulmonary vascular reactivity had been within the normal range for 32 healthy subjects. This man had high altitude pulmonary oedema despite currently recommended treatments for acute mountain sickness and normal pulmonary vascular reactivity to hypoxia at sea level.

摘要

一名40岁男子在攀登鲁文佐里山脉斯坦利山玛格丽塔峰(海拔5109米)过程中,于4000 - 5000米处出现严重肺水肿。他曾服用乙酰唑胺和高剂量地塞米松来治疗急性高原病症状。六年前,他作为健康志愿者在海平面进行低氧呼吸时接受了右心导管检查。他的肺血管反应性在32名健康受试者的正常范围内。尽管目前有针对急性高原病的推荐治疗方法,且他在海平面时对低氧的肺血管反应性正常,但该男子仍患上了高原肺水肿。

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Basic medical advice for travelers to high altitudes.高原旅行基本医疗建议。
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Doppler assessment of hypoxic pulmonary vasoconstriction and susceptibility to high altitude pulmonary oedema.低氧性肺血管收缩及高原肺水肿易感性的多普勒评估
Thorax. 1995 Jan;50(1):22-7. doi: 10.1136/thx.50.1.22.
3
Current prevention and management of acute mountain sickness.急性高原病的当前预防与管理
Yale J Biol Med. 1992 Jul-Aug;65(4):337-41.

本文引用的文献

1
Pulmonary edema of high altitude. II. Clinical, aerohemodynamic, and biochemical studies in a group with history of pulmonary edema of high altitude.
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2
Circulatory dynamics during high altitude pulmonary edema.高原肺水肿时的循环动力学
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3
Haemodynamic studies in high altitude pulmonary oedema.高原肺水肿的血流动力学研究。
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4
Abnormal circulatory responses to high altitude in subjects with a previous history of high-altitude pulmonary edema.有高原肺水肿既往史的受试者对高原的异常循环反应。
Circulation. 1971 Nov;44(5):759-70. doi: 10.1161/01.cir.44.5.759.
5
Increased lung vasoreactivity in children from Leadville, Colorado, after recovery from high-altitude pulmonary edema.科罗拉多州莱德维尔的儿童从高原肺水肿恢复后肺血管反应性增加。
Circulation. 1985 Nov;72(5):957-62. doi: 10.1161/01.cir.72.5.957.
6
Hypoxic pulmonary vasoconstriction and high altitude pulmonary edema.低氧性肺血管收缩与高原肺水肿
Am Rev Respir Dis. 1986 Aug;134(2):332-3. doi: 10.1164/arrd.1986.134.2.332.
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Hypoxic pulmonary vasoconstriction and pulmonary gas exchange in normal man.正常人体的低氧性肺血管收缩与肺气体交换
Respir Physiol. 1987 Apr;68(1):11-27. doi: 10.1016/0034-5687(87)90073-9.
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A randomized trial of dexamethasone and acetazolamide for acute mountain sickness prophylaxis.地塞米松和乙酰唑胺预防急性高原病的随机试验
Am J Med. 1987 Dec;83(6):1024-30. doi: 10.1016/0002-9343(87)90937-5.
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Current concepts. Acute mountain sickness.
N Engl J Med. 1988 Sep 29;319(13):841-5. doi: 10.1056/NEJM198809293191306.
10
High-altitude pulmonary edema. Characteristics of lung lavage fluid.高原肺水肿。肺灌洗液的特征。
JAMA. 1986 Jul 4;256(1):63-9.