Yoradjian Alessandra, Enokihara Mílvia Maria Simões e Silva, Paschoal Francisco Macedo
ABC School of Medicine, Santo André, SP, Brazil.
An Bras Dermatol. 2012 May-Jun;87(3):349-57; quiz 358-9. doi: 10.1590/s0365-05962012000300001.
Spitz and Reed nevi, also called spindle and/or epithelioid cell nevi, are a special group of melanocytic lesions due to their peculiar clinical, dermoscopic and histopathological features. The study of these nevi is of great interest because both their nomenclature and classification are still a matter of discussion. Most importantly, the difficulty to differentiate them from melanoma can lead to inadequate therapies. In this context, dermoscopy, a link between clinical and anatomopathological examinations, appears as a helpful diagnostic tool whose accuracy can reach 93%. "Borderline" lesions are still a great challenge and object of research, including molecular studies. The present study explores the relevant characteristics of these nevi, with emphasis on dermoscopic findings, aiming at understanding their natural history, as well as discussing treatment and patient follow-up.
斯皮茨痣和里德痣，也称为梭形和/或上皮样细胞痣，由于其独特的临床、皮肤镜和组织病理学特征，是一组特殊的黑素细胞病变。对这些痣的研究极具意义，因为它们的命名和分类仍存在争议。最重要的是，难以将它们与黑色素瘤区分开来可能导致治疗不当。在这种情况下，皮肤镜作为临床检查和解剖病理学检查之间的桥梁，是一种有用的诊断工具，其准确率可达93%。“临界”病变仍然是一个巨大的挑战和研究对象，包括分子研究。本研究探讨了这些痣的相关特征，重点是皮肤镜检查结果，旨在了解它们的自然病史，并讨论治疗和患者随访。
