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Stem-cell differentiation: Anchoring cell-fate cues.

作者信息

Chaudhuri Ovijit, Mooney David J

出版信息

Nat Mater. 2012 Jun 21;11(7):568-9. doi: 10.1038/nmat3366.

DOI:10.1038/nmat3366
PMID:22717486
Abstract
摘要

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Stem-cell differentiation: Anchoring cell-fate cues.干细胞分化：锚定细胞命运线索。
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Extracellular-matrix tethering regulates stem-cell fate.细胞外基质连接调控干细胞命运。
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One size does not fit all: developing a cell-specific niche for in vitro study of cell behavior.一刀切并不适用于所有情况：为细胞行为的体外研究开发特定细胞的微环境。
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Spatially patterned matrix elasticity directs stem cell fate.空间模式化的基质弹性引导干细胞命运。
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3D Decellularized Native Extracellular Matrix Scaffold for In Vitro Culture Expansion of Human Wharton's Jelly-Derived Mesenchymal Stem Cells (hWJ MSCs).用于人脐带华通氏胶源性间充质干细胞（hWJ MSCs）体外培养扩增的3D去细胞化天然细胞外基质支架
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Preparation of Cell-Derived Decellularized Matrices Mimicking Native ECM During the Osteogenesis and Adipogenesis of Mesenchymal Stem Cells.在间充质干细胞成骨和成脂过程中模拟天然细胞外基质的细胞源脱细胞基质的制备
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Differentiation of Induced Pluripotent Stem Cells towards Mesenchymal Stromal Cells is Hampered by Culture in 3D Hydrogels.三维水凝胶培养阻碍诱导多能干细胞向间充质基质细胞分化。
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1
Extracellular-matrix tethering regulates stem-cell fate.细胞外基质连接调控干细胞命运。
Nat Mater. 2012 May 27;11(7):642-9. doi: 10.1038/nmat3339.
2
Substrate viscosity enhances correlation in epithelial sheet movement.基质黏度增强了上皮片层运动的相关性。
Biophys J. 2011 Jul 20;101(2):297-306. doi: 10.1016/j.bpj.2011.05.048.
3
The influence of substrate creep on mesenchymal stem cell behaviour and phenotype.基底蠕动对间充质干细胞行为和表型的影响。
Sci Adv. 2023 Nov 3;9(44):eadf2664. doi: 10.1126/sciadv.adf2664.
4
From Protein Building Blocks to Functional Materials.从蛋白质构建单元到功能材料。
ACS Nano. 2021 Apr 27;15(4):5819-5837. doi: 10.1021/acsnano.0c08510. Epub 2021 Mar 24.
5
Consistent apparent Young's modulus of human embryonic stem cells and derived cell types stabilized by substrate stiffness regulation promotes lineage specificity maintenance.通过底物硬度调节稳定的人类胚胎干细胞和衍生细胞类型的一致表观杨氏模量促进谱系特异性维持。
Cell Regen. 2020 Sep 3;9(1):15. doi: 10.1186/s13619-020-00054-4.
6
Difference in biophysical properties of cancer-initiating cells in melanoma mutated zebrafish.黑色素瘤突变斑马鱼中肿瘤起始细胞的生物物理特性差异。
J Mech Behav Biomed Mater. 2020 Jul;107:103746. doi: 10.1016/j.jmbbm.2020.103746. Epub 2020 Apr 8.
7
Spatial distributions of pericellular stiffness in natural extracellular matrices are dependent on cell-mediated proteolysis and contractility.天然细胞外基质中细胞周围硬度的空间分布取决于细胞介导的蛋白水解作用和收缩性。
Acta Biomater. 2017 Jul 15;57:304-312. doi: 10.1016/j.actbio.2017.05.008. Epub 2017 May 5.
8
Integrating Concepts of Material Mechanics, Ligand Chemistry, Dimensionality and Degradation to Control Differentiation of Mesenchymal Stem Cells.整合材料力学、配体化学、维度和降解的概念以控制间充质干细胞的分化。
Curr Opin Solid State Mater Sci. 2016 Aug;20(4):171-179. doi: 10.1016/j.cossms.2016.04.001. Epub 2016 May 6.
9
On the determination of elastic moduli of cells by AFM based indentation.基于原子力显微镜压痕法测定细胞的弹性模量。
Sci Rep. 2017 Apr 3;7:45575. doi: 10.1038/srep45575.
10
Paracrine Effects of Adipose-Derived Stem Cells on Matrix Stiffness-Induced Cardiac Myofibroblast Differentiation via Angiotensin II Type 1 Receptor and Smad7.脂肪干细胞旁分泌作用通过血管紧张素 II 型 1 受体和 Smad7 对基质硬度诱导的心肌成纤维细胞分化的影响。
Sci Rep. 2016 Oct 5;6:33067. doi: 10.1038/srep33067.
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4
Modulus-driven differentiation of marrow stromal cells in 3D scaffolds that is independent of myosin-based cytoskeletal tension.三维支架中骨髓基质细胞的模量驱动分化，其独立于基于肌球蛋白的细胞骨架张力。
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5
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Nat Mater. 2010 Jun;9(6):518-26. doi: 10.1038/nmat2732. Epub 2010 Apr 25.
6
The effect of matrix stiffness on mesenchymal stem cell differentiation in a 3D thixotropic gel.基质硬度对 3D 触变凝胶中间充质干细胞分化的影响。
Biomaterials. 2010 Jan;31(3):385-91. doi: 10.1016/j.biomaterials.2009.09.057. Epub 2009 Oct 6.
7
Absence of filamin A prevents cells from responding to stiffness gradients on gels coated with collagen but not fibronectin.丝状肌动蛋白A的缺失会阻止细胞对涂有胶原蛋白而非纤连蛋白的凝胶上的硬度梯度做出反应。
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Directing osteogenic and myogenic differentiation of MSCs: interplay of stiffness and adhesive ligand presentation.引导间充质干细胞的成骨和成肌分化：硬度与黏附配体呈现的相互作用
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9
Matrix elasticity directs stem cell lineage specification.基质弹性引导干细胞谱系定向分化。
Cell. 2006 Aug 25;126(4):677-89. doi: 10.1016/j.cell.2006.06.044.
10
Local force and geometry sensing regulate cell functions.局部力和几何传感调节细胞功能。
Nat Rev Mol Cell Biol. 2006 Apr;7(4):265-75. doi: 10.1038/nrm1890.