Sedlmayr Peter, Blaschitz Astrid
Center for Molecular Medicine, Institute for Cell Biology, Histology and Embryology, Medical University of Graz, Graz, Austria.
Wien Med Wochenschr. 2012 May;162(9-10):214-9. doi: 10.1007/s10354-012-0082-3.
This review focuses on the placental expression of the tryptophan-degrading enzyme indoleamine 2,3-dioxygenase-1 (IDO1) and its potential roles, which may not only encompass immunosuppression and antimicrobial activity, but also vasodilation based on the endothelial expression on both sides of the feto-maternal interface.
本综述聚焦于色氨酸降解酶吲哚胺2,3-双加氧酶-1(IDO1)的胎盘表达及其潜在作用,其作用可能不仅包括免疫抑制和抗菌活性,还包括基于母胎界面两侧内皮表达的血管舒张作用。