Unit of Translational Medicine, Department of Immunology and Rheumatology, Nagasaki University, Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki 852-8501, Japan.
Mod Rheumatol. 2013 May;23(3):572-6. doi: 10.1007/s10165-012-0684-z. Epub 2012 Jun 21.
A 22-year-old female with ulcerative colitis that was successfully treated with infliximab (IFX), and remained stable following tapered discontinuation of prednisolone, developed anterior neck pain and elevation of C-reactive protein following her fourth administration of IFX. She was diagnosed with Takayasu arteritis (TA) based on neck ultrasound and computed tomography angiography. This is the first report describing the development of TA during treatment of UC with IFX.
一位 22 岁女性患有溃疡性结肠炎，经英夫利昔单抗（IFX）治疗后成功缓解，泼尼松龙逐渐减量后病情稳定。在第四次接受 IFX 治疗后，她出现前颈部疼痛和 C 反应蛋白升高。根据颈部超声和计算机断层血管造影检查，诊断为 Takayasu 动脉炎（TA）。这是首例描述在使用 IFX 治疗 UC 期间发生 TA 的报告。
