Division of Rheumatology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
Korean J Intern Med. 2013 Jul;28(4):491-6. doi: 10.3904/kjim.2013.28.4.491. Epub 2013 Jul 1.
Takayasu arteritis (TA) is a chronic vasculitis that affects the aortic arch and its primary branches. Ulcerative colitis (UC) is an inflammatory bowel disease of unknown etiology. Patients diagnosed with both TA and UC have rarely been reported. The pathogenesis of TA and UC is uncertain, but cell-mediated mechanisms play an important role in both diseases, and a genetic factor is thought to have an effect on the coincidence of these two diseases. We herein report a 38-year-old female with TA who had a history of UC with optic neuritis. We believe that this is the first case of the coexistence of TA and UC in Korea.
Takayasu 动脉炎（TA）是一种慢性血管炎，影响主动脉弓及其主要分支。溃疡性结肠炎（UC）是一种病因不明的炎症性肠病。同时患有 TA 和 UC 的患者很少见。TA 和 UC 的发病机制尚不清楚，但细胞介导的机制在这两种疾病中都起着重要作用，并且遗传因素被认为对这两种疾病的同时发生有影响。我们在此报告了一例 38 岁女性 TA 患者，该患者有 UC 合并视神经炎病史。我们认为这是韩国首例 TA 和 UC 共存的病例。
