Zhao Guixiang, Li Chaoyang, Ford Earl S, Tsai James, Dhingra Satvinder S, Croft Janet B, McKnight-Eily Lela R, Balluz Lina S
Division of Behavioral Surveillance, Public Health Surveillance Program Office, Office of Surveillance, Epidemiology and Laboratory Services, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA.
J Obes. 2012;2012:263142. doi: 10.1155/2012/263142. Epub 2012 Jun 6.
Obesity is associated with increased risks for mental disorders. This study examined associations of obesity indicators including body mass index (BMI), waist circumference, and waist-height ratio with suicidal ideation among U.S. women. We analyzed data from 3,732 nonpregnant women aged ≥20 years who participated in the 2005-2008 National Health and Nutrition Examination Survey. We used anthropometric measures of weight, height, and waist circumference to calculate BMI and waist-height ratio. Suicidal ideation was assessed using the Item 9 of the Patient Health Questionnaire-9. Odds ratios with 95% conference intervals were estimated using logistic regression analyses after controlling for potential confounders. The age-adjusted prevalence of suicidal ideation was 3.0%; the prevalence increased linearly across quartiles of BMI, waist circumference, and waist-height ratio (P for linear trend <0.01 for all). The positive associations of waist circumference and waist-height ratio with suicidal ideation remained significant (P < 0.05) after adjustment for sociodemographics, lifestyle-related behavioral factors, and having either chronic conditions or current depression. However, these associations were attenuated after both chronic conditions and depression were entered into the models. Thus, the previously reported association between obesity and suicidal ideation appears to be confounded by coexistence of chronic conditions and current depression among women of the United States.
肥胖与精神障碍风险增加有关。本研究调查了肥胖指标(包括体重指数(BMI)、腰围和腰高比)与美国女性自杀意念之间的关联。我们分析了3732名年龄≥20岁的非妊娠女性的数据,这些女性参与了2005 - 2008年国家健康和营养检查调查。我们使用体重、身高和腰围的人体测量指标来计算BMI和腰高比。自杀意念通过患者健康问卷 - 9的第9项进行评估。在控制潜在混杂因素后,使用逻辑回归分析估计具有95%置信区间的比值比。年龄调整后的自杀意念患病率为3.0%;自杀意念患病率在BMI、腰围和腰高比的四分位数中呈线性增加(所有线性趋势的P值均<0.01)。在调整了社会人口统计学、生活方式相关行为因素以及患有慢性疾病或当前抑郁情况后,腰围和腰高比与自杀意念的正相关仍然显著(P<0.05)。然而,在将慢性疾病和抑郁情况都纳入模型后,这些关联减弱了。因此,先前报道的肥胖与自杀意念之间的关联似乎被美国女性中慢性疾病和当前抑郁情况的共存所混淆。