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细胞毒性 T 淋巴细胞：狙击癌症干细胞。

Cytotoxic T lymphocytes: Sniping cancer stem cells.

机构信息

Department of Pathology; Sapporo Medical University School of Medicine; Sapporo, Japan.

出版信息

Oncoimmunology. 2012 Jan 1;1(1):123-125. doi: 10.4161/onci.1.1.18075.

DOI:10.4161/onci.1.1.18075
PMID:22720232
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3376951/
Abstract

Cancer stem cells (CSCs)/cancer-initiating cells (CICs) are characterized as a small population of cancer cells that have high tumor-initiating ability. CSCs/CICs are resistant to several cancer therapies, and eradication of CSCs/CICs is essential to cure cancer. How can we eradicate CSCs/CICs? Cytotoxic T lymphocytes (CTLs) might be a promising answer.

摘要

肿瘤干细胞（CSCs）/癌症起始细胞（CICs）的特征是一小部分具有高肿瘤起始能力的癌细胞。CSCs/CICs 对几种癌症疗法具有抗性，因此根除 CSCs/CICs 对于治愈癌症至关重要。我们如何才能根除 CSCs/CICs 呢？细胞毒性 T 淋巴细胞（CTLs）可能是一个有前途的答案。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f05/3376951/146ff3cd73ca/onci-1-123-g1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f05/3376951/146ff3cd73ca/onci-1-123-g1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f05/3376951/146ff3cd73ca/onci-1-123-g1.jpg

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本文引用的文献

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Cytotoxic T lymphocytes efficiently recognize human colon cancer stem-like cells.细胞毒性 T 淋巴细胞能有效地识别人类结肠癌细胞样干细胞。
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