Ayoub S, Monin G, Rock E, Younes A
Institut National de Recherche Agronomique (INRA), Ceyrat, France.
Cell Biochem Funct. 1990 Oct;8(4):205-10. doi: 10.1002/cbf.290080404.
Oxygen consumption was depressed in mitochondria isolated from halothane sensitive pig (HP) muscle. The calculation of the respiratory control ratio (RCR) indicated that mitochondria were more affected at the site-I level of the respiratory chain. Calcium accumulation in these mitochondria was not altered when driven by the oxidation of succinate. This process was abolished when linked to ATP as a source of energy. ATP transport was completely inhibited in (HP) mitochondria.
从氟烷敏感猪(HP)肌肉中分离出的线粒体耗氧量降低。呼吸控制率(RCR)的计算表明,线粒体在呼吸链的位点I水平受到的影响更大。当由琥珀酸氧化驱动时,这些线粒体中的钙积累没有改变。当与ATP作为能量来源相联系时,这个过程被消除。ATP转运在(HP)线粒体中被完全抑制。