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产后嗜酸性粒细胞性胃肠炎一例并文献复习。

A case of postpartum eosinophilic gastroenteritis and review of the literature.

机构信息

Division of Gastroenterology, Department of Internal Medicine, University Hospital Rijeka, Croatia.

出版信息

Dig Dis. 2012;30(2):232-5. doi: 10.1159/000336711. Epub 2012 Jun 20.

Abstract

Eosinophilic gastroenteritis (EG) is a rare disease of unknown etiology that can involve any area of the gastrointestinal (GI) tract. It can be classified into three major types: predominantly mucosal, muscularis, or subserosal form. Diagnosis of EG is confirmed after the exclusion of other disorders having similar features, such as parasitic infection, carcinoma, allergy, and autoimmune conditions such as Churg-Strauss disease. Correct diagnosis hinges on the presence of eosinophilic infiltration of one or more areas of the GI tract, without extraintestinal involvement. We present the case of a 30-year-old female with symptoms of EG 26 days after delivery. After corticosteroid and montelukast treatment for 2 weeks, all symptoms and objective clinical findings disappeared. Although numerous cases of this disorder have been described, to our knowledge this is the first case of postpartum EG. This case highlights the need to include this entity in the differential diagnosis of postpartum GI disorders.

摘要

嗜酸粒细胞性胃肠炎(EG)是一种病因不明的罕见疾病,可累及胃肠道(GI)的任何区域。它可以分为三种主要类型:主要是黏膜型、肌层型或浆膜下层型。EG 的诊断是在排除具有相似特征的其他疾病(如寄生虫感染、癌、过敏和自身免疫性疾病如 Churg-Strauss 病)后确认的。正确的诊断取决于 GI 一个或多个区域存在嗜酸性粒细胞浸润,而无肠外受累。我们报告了一例 30 岁女性,在分娩后 26 天出现 EG 症状。在接受皮质类固醇和孟鲁司特治疗 2 周后,所有症状和客观临床发现均消失。尽管已经描述了许多这种疾病的病例,但据我们所知,这是首例产后 EG。该病例强调需要将这种疾病纳入产后胃肠道疾病的鉴别诊断。

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