Department of Neurology, St. Josef Hospital Bochum, Gudrunstr. 56, 44791 Bochum, Germany.
J Neural Transm (Vienna). 2013 Feb;120(2):309-13. doi: 10.1007/s00702-012-0848-1. Epub 2012 Jun 22.
Disturbances of alternating movement execution are a characteristic clinical sign of patients with Parkinson's disease (PD). Objectives were to compare instrumentally measured diadochokinetic motion series carrying out before and 1 h after standardised levodopa intake and to correlate the device results with the respective rating scores of the PD patients. Maximum velocity and interval improved following levodopa application. The amplitude of motions did not differ between both assessment moments. Closer correlations between rating- and diadochokinesimeter outcomes appeared before levodopa intake.
交替运动执行障碍是帕金森病 (PD) 患者的一个特征性临床征象。目的是比较标准化左旋多巴摄入前后仪器测量的交替运动系列，并将设备结果与 PD 患者的相应评分进行相关性分析。最大速度和间隔在左旋多巴应用后得到改善。两种评估时刻的运动幅度没有差异。在服用左旋多巴之前，评分和交替运动计结果之间的相关性更强。
