Department of Neurology, St. Joseph Hospital Berlin, Weissensee, Gartenstr. 1, 13088 Berlin, Germany.
J Neural Transm (Vienna). 2010 Feb;117(2):189-95. doi: 10.1007/s00702-009-0336-4. Epub 2009 Nov 10.
Instrumental motion assessment, i.e., peg insertion, gains importance as an addition to rating procedures to determine the efficacy of therapeutic interventions and to serve as diagnostic tool in patients with Parkinson's disease (PD). One of their motor features is disturbed execution of alternating motions. The objectives of the study were to assess pronation and supination of the forearms and peg insertion with instruments and to correlate the outcomes with rating scores in PD patients. Controls and 27 idiopathic PD patients, taken off treatment for 12 h, were scored and performed on both devices. PD patients showed a reduced maximum velocity (v), performance interval and amplitude of diadochokinetic movements than controls. V outcomes showed closer associations to rated motor behavior, in particular akinesia and rigidity, and peg insertion results than amplitude, respectively periods of diadochokinetic motion sequences. This altered performance of diadochokinetic movements corresponds to the clinical motor symptoms of PD patients and differs from healthy controls.
器械运动评估，即插栓，作为评估治疗干预效果的评分程序的补充以及帕金森病（PD）患者的诊断工具变得越来越重要。其运动特征之一是交替运动的执行受到干扰。本研究的目的是评估前臂的旋前和旋后以及使用器械进行插栓，并将结果与 PD 患者的评分进行相关分析。对照组和 27 名特发性 PD 患者在停止治疗 12 小时后，分别在两种设备上进行评分和测试。PD 患者的最大速度（v）、动作间隔和快复动作运动的幅度比对照组小。v 结果与运动行为的评定，特别是运动迟缓和僵硬，以及与 peg 插入结果的相关性比与快复动作运动序列的幅度、周期的相关性更密切。快复动作运动的这种改变的性能与 PD 患者的临床运动症状相对应，与健康对照组不同。
