Joebges M, Mrowka M, Schimke N, Shing M, Dengler R, Odin P
Neurological Rehabilitation Centre, Leipzig, Germany.
Acta Neurol Scand. 2003 Dec;108(6):415-23. doi: 10.1034/j.1600-0404.2003.00161.x.
Considering the rapid appearance of new pharmaceutical and surgical treatments for Parkinson's disease, a development of quantitative and objective methods for measuring treatment effects is highly warranted. The purpose of this study was to investigate the usability of a computerized movement analysis system in Parkinson's disease patients.
We analysed the effect of L-dopa in a group of 14 patients with idiopathic Parkinson's disease and compared the results to those of 14 control persons. The results were compared to those achieved with the UPDRS, Hoehn & Yahr and Schwab & England Scales, as well as, to time-measured manual testing according to the CAPIT and CAPSIT-PD protocols.
We found that the computerized analysis results correlated well with the findings obtained with traditional scales and manual techniques, and that the computer-analysis had the advantage of delivering more exact and quantitative information not only concerning movement speed but also aspects of movement quality.
We conclude that this form of computerized movement analysis can have an important role in evaluating the effect of treatments, individualizing the therapy, as well as, for diagnostic procedures in patients with Parkinson symptomatology.
鉴于帕金森病新的药物和手术治疗方法迅速出现，非常有必要开发定量和客观的方法来衡量治疗效果。本研究的目的是调查计算机化运动分析系统在帕金森病患者中的可用性。
我们分析了左旋多巴对一组14例特发性帕金森病患者的影响，并将结果与14名对照者的结果进行比较。将结果与使用统一帕金森病评定量表（UPDRS）、 Hoehn & Yahr分级量表和Schwab & England量表所获得的结果进行比较，同时也与根据CAPIT和CAPSIT-PD方案进行的定时手动测试结果进行比较。
我们发现计算机化分析结果与传统量表和手动技术所获得的结果密切相关，并且计算机分析不仅在运动速度方面，而且在运动质量方面都具有提供更精确和定量信息的优势。
我们得出结论，这种形式的计算机化运动分析在评估治疗效果、使治疗个体化以及对有帕金森症状的患者进行诊断程序方面可以发挥重要作用。
