Elucidating the temporal order of silencing.
作者信息
Izaurralde Elisa
机构信息
Department of Biochemistry, Max Planck Institute for Developmental Biology, Tübingen, Germany.
出版信息
EMBO Rep. 2012 Aug;13(8):662-3. doi: 10.1038/embor.2012.91. Epub 2012 Jun 22.
Abstract
摘要
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2
miRNA-mediated gene silencing by translational repression followed by mRNA deadenylation and decay.miRNA 介导的基因沉默通过翻译抑制 followed by mRNA 去腺苷酸化和降解。
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3
Ribosome profiling shows that miR-430 reduces translation before causing mRNA decay in zebrafish.核糖体图谱分析表明，miR-430 在导致 zebrafish 中 mRNA 降解之前降低了翻译。
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