Baumeister Alan A, Henderson Kristopher, Pow Joni Lee, Advokat Claire
Department of Psychology, Louisiana State University, Baton Rouge, LA, USA.
J Hist Neurosci. 2012 Jul;21(3):263-79. doi: 10.1080/0964704X.2011.595649.
Research on the neurobiology and pharmacotherapy of attention-deficit/hyperactivity disorder (ADHD) has grown exponentially since 1980. A reasonable question is whether this research has improved our understanding and treatment of ADHD. This article describes relevant developments that took place roughly between 1900 and 1970. During this time, the efficacy of stimulant therapy for the disorder was established and the symptoms of ADHD were linked to many possible nervous system disorders including in the brain-stem, reticular formation, diencephalon, basal ganglia, frontal lobes, and cortex. In 1970, the catecholamine hypothesis of ADHD was proposed. It is concluded that early theories about the neurobiologic basis of ADHD anticipated core ideas of modern theory.
自1980年以来，关于注意力缺陷多动障碍（ADHD）的神经生物学和药物治疗的研究呈指数级增长。一个合理的问题是，这项研究是否增进了我们对ADHD的理解和治疗。本文描述了大约在1900年至1970年间发生的相关进展。在此期间，确立了兴奋剂疗法对该疾病的疗效，并且ADHD的症状与许多可能的神经系统疾病有关，包括脑干、网状结构、间脑、基底神经节、额叶和皮质。1970年，提出了ADHD的儿茶酚胺假说。得出的结论是，关于ADHD神经生物学基础的早期理论预见了现代理论的核心观点。
