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采用来自金黄色酿脓葡萄球菌和兔肌肉的果糖 1,6-二磷酸醛缩酶一锅四酶合成酮糖。

One-pot four-enzyme synthesis of ketoses with fructose 1,6-bisphosphate aldolases from Staphylococcus carnosus and rabbit muscle.

机构信息

National Glycoengineering Research Center, The State Key Laboratory of Microbial Technology, Shandong University, Jinan, Shandong 250100, China.

出版信息

Carbohydr Res. 2012 Aug 1;357:143-6. doi: 10.1016/j.carres.2012.05.007. Epub 2012 May 15.

Abstract

By the action of D-fructose 1,6-bisphosphate aldolases (FruA) from rabbit muscle and Staphylococcus carnosus, various ketoses were synthesized from glyceraldehydes or other aliphatic aldehydes as acceptors in a one-pot four-enzyme system.

摘要

在兔肌肉和肉状球菌的 D-果糖-1,6-二磷酸醛缩酶(FruA)的作用下,各种酮糖可以从甘油醛或其他脂肪醛作为受体,在一锅四酶体系中合成。

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本文引用的文献

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Appl Microbiol Biotechnol. 2007 May;75(1):33-45. doi: 10.1007/s00253-007-0882-3. Epub 2007 Feb 22.
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Curr Opin Biotechnol. 2003 Dec;14(6):570-6. doi: 10.1016/j.copbio.2003.10.004.
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Class I aldolases: substrate specificity, mechanism, inhibitors and structural aspects.
Prog Biophys Mol Biol. 1995;63(3):301-40. doi: 10.1016/0079-6107(95)00008-9.

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