来自查氏青霉的新型抗线虫和抗寄生虫剂。I. 发酵、分离及生物活性。
Novel antinematodal and antiparasitic agents from Penicillium charlesii. I. Fermentation, isolation and biological activity.
作者信息
Ondeyka J G, Goegelman R T, Schaeffer J M, Kelemen L, Zitano L
机构信息
Merck & Co., Inc., Rahway, New Jersey 07065-0900.
出版信息
J Antibiot (Tokyo). 1990 Nov;43(11):1375-9. doi: 10.7164/antibiotics.43.1375.
PMID:2272914
Abstract
Paraherquamide and six novel analogs were isolated from the fermentation of Penicillium charlesii (ATCC 20841). All seven natural products displayed potent antinematodal activity against Caenorhabditis elegans. None of the novel analogs were more potent than paraherquamide.
摘要
从产黄青霉（ATCC 20841）的发酵产物中分离出了副赫曲霉素及其六种新型类似物。所有这七种天然产物均对秀丽隐杆线虫显示出强大的抗线虫活性。没有一种新型类似物的活性比副赫曲霉素更强。
Zotero 插件