Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 10 Center Drive, CRC, Rm B3 4141, MSC 1684, Bethesda, MD 20892-1684, USA.
J Clin Immunol. 2012 Dec;32(6):1400-3. doi: 10.1007/s10875-012-9726-8. Epub 2012 Jun 24.
Rothia aeria caused a necrotic lymphadenitis and neck abscess in a patient with CGD. This infection was aggressive, crossed tissue planes, required two surgeries, as well as prolonged antibiotics for complete resolution. Rothia aeria is a rare pathogen that can be added to the spectrum of agents causing disease in CGD, a finding that further reinforces the importance of microbiologic identification of infections in this patient population.
嗜麦芽窄食单胞菌导致 CGD 患者发生坏死性淋巴结炎和颈部脓肿。这种感染具有侵袭性,可跨越组织间隙,需要进行两次手术以及长时间使用抗生素才能完全解决。嗜麦芽窄食单胞菌是一种罕见的病原体,可加入导致 CGD 发病的病原体谱中,这一发现进一步强调了对该患者人群感染进行微生物鉴定的重要性。