用毛细管气相色谱法检测和定量环氧乙烷、2-氯乙醇和乙二醇。

Detection and quantitation of ethylene oxide, 2-chloroethanol, and ethylene glycol with capillary gas chromatography.

作者信息

Danielson J W, Snell R P, Oxborrow G S

机构信息

Food and Drug Administration, Sterility Analysis Research Center, Minneapolis, Minnesota 55455.

出版信息

J Chromatogr Sci. 1990 Mar;28(3):97-101. doi: 10.1093/chromsci/28.3.97.

DOI:10.1093/chromsci/28.3.97

PMID:2273068

Abstract

A procedure is described for detection and quantitation of ethylene oxide and two major reaction products. Detection of ethylene oxide residuals extracted from alcohol pads (cellulose) and plastic material is illustrated. Quantitation of the three compounds can be obtained with a single gas chromatographic (GC) analysis. A DB-Wax-30N, 0.25 mm i.d. column is used with 1:50 split injections with dimethylformamide as the solvent and 1:100 split injections with water as the solvent. A DB-Wax-30W, 0.32 mm i.d. column is used for on-column injections and 1:100 split water injections. Linearity of the three compounds is demonstrated.

摘要

本文描述了一种用于检测和定量环氧乙烷及其两种主要反应产物的方法。文中展示了从酒精垫（纤维素）和塑料材料中提取的环氧乙烷残留量的检测方法。通过单次气相色谱（GC）分析即可对这三种化合物进行定量。使用内径为0.25 mm的DB-Wax-30N色谱柱，以二甲基甲酰胺为溶剂进行1:50分流进样，以水为溶剂进行1:100分流进样。使用内径为0.32 mm的DB-Wax-30W色谱柱进行柱上进样和1:100分流的水进样。文中还证明了这三种化合物的线性关系。