Schreiber M M, Moon T E, Fox S H, Davidson J
Department of Family and Community Medicine, University of Arizona College of Medicine, Tucson.
J Am Acad Dermatol. 1990 Dec;23(6 Pt 1):1114-8. doi: 10.1016/0190-9622(90)70343-g.
Data from the Southeast Arizona Skin Cancer Registry collected during 1985 through June 1988 were used in this study. Patients who had a nonmelanoma skin cancer (basal cell or squamous cell carcinoma) removed in 1985 were observed until subsequent nonmelanoma skin cancers developed or until June 30, 1988. Twelve categories of nonmelanoma skin cancers were developed on the basis of the type of first nonmelanoma skin cancer and type of second, third, and fourth nonmelanoma skin cancers. Analyses showed the highest risk of a subsequent nonmelanoma skin cancer developing was within 1 year (36.39%), the rate of developing another nonmelanoma skin cancer depended on type (squamous cell carcinoma, 100%; basal cell carcinoma, 44.23% to 83.65%), and total risk decreased during the 1277 days of the study.
本研究使用了1985年至1988年6月期间从亚利桑那州东南部皮肤癌登记处收集的数据。1985年接受非黑色素瘤皮肤癌（基底细胞癌或鳞状细胞癌）切除手术的患者，被观察至后续非黑色素瘤皮肤癌出现或至1988年6月30日。根据首例非黑色素瘤皮肤癌的类型以及第二、第三和第四例非黑色素瘤皮肤癌的类型，划分出了12种非黑色素瘤皮肤癌类别。分析表明，后续发生非黑色素瘤皮肤癌的最高风险出现在1年内（36.39%），发生另一种非黑色素瘤皮肤癌的几率取决于类型（鳞状细胞癌为100%；基底细胞癌为44.23%至83.65%），且在为期1277天的研究期间，总体风险有所下降。
