Bertozzi Nicolò, Simonacci Francesco, Greco Michele Pio, Grignaffini Eugenio, Raposio Edoardo
Department of Medicine and Surgery, Plastic Surgery Division, University of Parma, Parma, Italy; Cutaneous, Mini-invasive, Regenerative and Plastic Surgery Unit, Parma University Hospital, Parma, Italy..
Acta Biomed. 2019 Jan 22;90(1):77-82. doi: 10.23750/abm.v90i1.6395.
Basal Cell Carcinoma (BCC) alone accounts for 80% of cases of non-melanoma skin cancer (NMSC), which characteristically develops on sun-exposed skin. Indeed the most common site of BCC is the head and neck region (80%). The purpose of this study to review the experience of our center with BCC in the head and neck region to report the sites of occurrence and treatment.
We retrospectively reviewed 77 patients with BCC of the head and neck, who revived surgical treatment within our plastic surgery division. Basic demographic data, cancer site and size, surgical treatment and histological data were collected. The mean follow-up period was 12 months.
The study population included 37 males and 40 females, with a mean age of 74.12 years. The nasal unit was the main site of BCC (31.82%), followed by the periorbital (13.64%) and cervical (12.5%) units. Primary closure was the main surgical procedure performed (72.5%), followed by local flap (26.1%) and full-thickness skin grafts (1.4%). The safety resection margin ranged from 4.5 to 9 mm, with a 98.7% complete removal rate. Neither recurrence nor any newly-developed lesions were reported during follow-up in any patient.
Our work reflects the shift in the incidence of BCC, which now seems to be more frequent in females. Furthermore, our data strengthens the association between UVR exposure and BCC, confirms its predilection to occur on the nasal unit and validates surgical excision as the gold standard treatment for skin cancer.
基底细胞癌（BCC）单独占非黑色素瘤皮肤癌（NMSC）病例的80%，其特征是在暴露于阳光的皮肤上发展。实际上，BCC最常见的部位是头颈部区域（80%）。本研究的目的是回顾我们中心对头颈部BCC的治疗经验，报告其发生部位和治疗方法。
我们回顾性分析了77例头颈部BCC患者，他们在我们整形外科接受了手术治疗。收集了基本人口统计学数据、癌症部位和大小、手术治疗及组织学数据。平均随访期为12个月。
研究人群包括37名男性和40名女性，平均年龄为74.12岁。鼻部是BCC的主要发生部位（31.82%），其次是眶周（13.64%）和颈部（12.5%）。主要的手术方式是一期缝合（72.5%），其次是局部皮瓣（26.1%）和全厚皮片移植（1.4%）。安全切缘范围为4.5至9毫米，完全切除率为98.7%。随访期间，所有患者均未报告复发或任何新出现的病变。
我们的工作反映了BCC发病率的变化，现在女性中似乎更常见。此外，我们的数据加强了紫外线暴露与BCC之间的关联，证实了其在鼻部的偏好，并验证了手术切除作为皮肤癌的金标准治疗方法。
