Qi Zhengyan, Middleton James W, Malcolm Allison
Neurogastroenterology Unit and Department of Gastroenterology, Royal North Shore Hospital, Reserve Road, St Leonards, NSW, 2065, Australia.
The University of Sydney, Sydney, Australia.
Curr Gastroenterol Rep. 2018 Aug 29;20(10):47. doi: 10.1007/s11894-018-0655-4.
To evaluate and report current evidence regarding the management of bowel dysfunction in spinal cord injury. There is a paucity of high-quality large studies on which to base management advice.
Recent research has focused on defining the nature of symptomatology of bowel dysfunction in SCI and describing the effects on quality of life and social interactions. Technical aspects of colonoscopy have received attention, and aspects of understanding the pathophysiology in relation to both neural and non-neural dysfunction have been studied. There has been refinement and expansion of the pharmacological and non-pharmacological treatment options for bowel dysfunction in SCI. Management of bowel dysfunction in SCI requires a comprehensive and individualized approach, encompassing lifestyle, toileting routine, stimulation, diet, medications, and surgery. Further high-quality research is required to inform best practice.
评估并报告目前关于脊髓损伤后肠道功能障碍管理的证据。缺乏高质量的大型研究作为管理建议的依据。
近期研究聚焦于明确脊髓损伤后肠道功能障碍症状学的本质，以及描述其对生活质量和社交互动的影响。结肠镜检查的技术方面受到关注，并且对与神经和非神经功能障碍相关的病理生理学的理解也进行了研究。脊髓损伤后肠道功能障碍的药物和非药物治疗选择得到了改进和扩展。脊髓损伤后肠道功能障碍的管理需要综合且个体化的方法，包括生活方式、排便习惯、刺激、饮食、药物和手术。需要进一步的高质量研究以指导最佳实践。
