Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
Bone Marrow Transplant. 2013 Apr;48(4):469-73. doi: 10.1038/bmt.2012.123. Epub 2012 Jun 25.
Currently, more than 40000 patients undergo allogeneic hematopoietic SCT (HSCT) annually throughout the world, and the numbers are increasing rapidly. Long-term survival after allogeneic-HSCT (allo-HSCT) has also improved significantly since its inception over 40 years ago due to improved supportive care and early recognition of long-term complications. In long-term follow-up after transplantation, the focus of care moves beyond cure of the original disease to late effects and quality of life. Nearly one-fourth of the long-term survivors are likely to have chronic consequences of HSCT, which require frequent help by caregivers, particularly informal caregivers such as spouses, partners or children. The physical and psychosocial consequences for patients undergoing HSCT have been extensively reported. There has, however, been far less investigation into the long-term follow-up of caregivers of HSCT recipients. This article provides an overview on addressing caregiver issues after HSCT. The rapidly growing population of long-term HSCT survivors creates an obligation not only to educate patients and physicians about the late complications observed in patients but also to follow up caregivers for their psychosocial support needs.
目前，全世界每年有超过 40000 例患者接受异基因造血干细胞移植（HSCT），且这一数字还在迅速增加。自 40 多年前异基因-HSCT（allo-HSCT）问世以来，由于支持性治疗的改善和对长期并发症的早期认识，其长期存活率也得到了显著提高。在移植后的长期随访中，护理的重点不再仅仅是治愈原发病，而是关注长期影响和生活质量。近四分之一的长期幸存者可能会出现 HSCT 的慢性后果，这需要护理人员（尤其是配偶、伴侣或子女等非正式护理人员）经常提供帮助。接受 HSCT 的患者的身体和社会心理后果已得到广泛报道。然而，对 HSCT 受者护理人员的长期随访的研究却少得多。本文概述了 HSCT 后如何解决护理人员的问题。长期 HSCT 幸存者人数的迅速增加，不仅使我们有义务教育患者和医生了解患者中观察到的晚期并发症，还需要关注护理人员的社会心理支持需求。
