Spine Surgery, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, China.
Eur Spine J. 2012 Oct;21(10):2050-8. doi: 10.1007/s00586-012-2409-6. Epub 2012 Jun 26.
Previous studies had shown that sagittal spinal and pelvic morphology may be associated with the development and progression of adolescent idiopathic scoliosis, but the predictive value of initial spinal and pelvic morphology on the curve progression during brace treatment is unknown. The objective of this study was to evaluate the relation between initial spinopelvic morphology and the risk of curve progression of adolescent idiopathic scoliosis with the Milwaukee brace.
From 2002 to 2007, adolescent idiopathic scoliosis (single thoracic curve with apex at or above T8) was treated with the Milwaukee brace in 60 girls. Initial standing, full-length lateral radiographs were made and seven sagittal radiographic parameters of spinal and pelvic alignment were measured. Patients were followed until skeletal maturity or progression of Cobb angle >45°. The progression of curve was defined as an increase of Cobb angle ≥6° at final follow-up or progression to surgery during brace treatment.
The 45 patients (75.0 %) who had successful control of curve progression were initially significantly more skeletally mature (higher mean Risser sign) than the 15 patients (25.0 %) who had curve progression. The initial mean Cobb angle was similar between the stable and progressed groups. The mean pelvic tilt, T1-spinopelvic inclination and T9-spinopelvic inclination angles were significantly greater in the stable group than in the progressed group and these three angles were independent predictors for curve progression during brace treatment. There were no significant differences between the stable and progressed groups in initial mean pelvic incidence, sacral slope, thoracic kyphosis or lumbar lordosis angles. Pre-bracing pelvic tilt ≤-0.5° was strongly predictive and T1-spinopelvic inclination ≤3.5° was moderately predictive of curve progression during the Milwaukee brace treatment.
Initial pelvic tilt and spinopelvic inclination angles may predict the curve progression and treatment outcome of adolescent idiopathic scoliosis with the Milwaukee brace.
既往研究表明矢状位脊柱和骨盆形态可能与青少年特发性脊柱侧凸的发生和进展有关,但初始脊柱和骨盆形态对支具治疗过程中曲线进展的预测价值尚不清楚。本研究的目的是评估 Milwaukee 支具治疗青少年特发性脊柱侧凸时初始脊柱骨盆形态与曲线进展风险之间的关系。
2002 年至 2007 年,60 例女性青少年特发性脊柱侧凸(单一胸弯,顶椎位于 T8 或以上)采用 Milwaukee 支具治疗。患者均接受初始站立位全长侧位片,测量 7 项脊柱和骨盆矢状位参数。患者随访至骨骼成熟或 Cobb 角进展>45°。定义曲线进展为最终随访时 Cobb 角增加≥6°或支具治疗期间进展至手术。
45 例(75.0%)患者获得成功的曲线控制,其初始时骨骼成熟度明显更高(Risser 征更高),而 15 例(25.0%)患者出现曲线进展。稳定组和进展组的初始 Cobb 角均值相似。稳定组的骨盆倾斜角、T1 椎体-骨盆倾斜角和 T9 椎体-骨盆倾斜角显著大于进展组,这三个角度是支具治疗过程中曲线进展的独立预测因素。稳定组和进展组之间的初始平均骨盆入射角、骶骨倾斜角、胸腰椎后凸角和腰椎前凸角无显著差异。支具治疗前骨盆倾斜角≤-0.5°有很强的预测价值,T1 椎体-骨盆倾斜角≤3.5°有中度预测价值。
初始骨盆倾斜角和脊柱骨盆倾斜角可能预测 Milwaukee 支具治疗青少年特发性脊柱侧凸的曲线进展和治疗结果。