Department of Periodontology, Kagoshima University, Graduate School of Medical and Dental Sciences, Kagoshima, Japan.
Oral Surg Oral Med Oral Pathol Oral Radiol. 2012 Jul;114(1):35-42. doi: 10.1016/j.tripleo.2011.05.028. Epub 2011 Aug 24.
The present study evaluated the effects of bone swaging (BS) with injectable calcium phosphate bone cement (CPC) on periodontal healing in 1-wall intrabony defects in dogs.
Surgically created 1-wall intrabony defects were treated with BS, CPC, BS with CPC (BS/CPC), or open-flap debridement (OFD). The animals were humanely killed for histologic evaluation at 8 weeks.
New bone formation occurred from the host bone toward the coronal region of the defects in the BS/CPC group. The height of new bone formation was significantly higher in the BS/CPC group than in the other groups (P < .05). New cementum formation was most notable in the BS/CPC group, where it was significantly greater than in the OFD and CPC groups (P < .05).
Within the limitations of the present study, it was concluded that BS/CPC treatment effectively promoted new bone and cementum formation in 1-wall intrabony defects in dogs.
本研究评估了在骨挤压（BS）联合注射型磷酸钙骨水泥（CPC）治疗犬 1 壁型骨内缺损中的牙周愈合效果。
采用手术方法制备 1 壁型骨内缺损，分别采用 BS、CPC、BS 联合 CPC（BS/CPC）或翻瓣清创术（OFD）治疗。在 8 周时，通过人道处死动物进行组织学评估。
BS/CPC 组的新骨从宿主骨向缺损的冠方区域形成。BS/CPC 组的新骨形成高度明显高于其他组（P<.05）。BS/CPC 组的新牙骨质形成最为显著，明显大于 OFD 和 CPC 组（P<.05）。
在本研究的限制范围内，可以得出结论，BS/CPC 治疗可有效促进犬 1 壁型骨内缺损中新骨和牙骨质的形成。
