磷酸钙骨水泥骨压痕对犬牙周再生的影响。
Effect of bone swaging with calcium phosphate bone cement on periodontal regeneration in dogs.
机构信息
Department of Periodontology, Kagoshima University, Graduate School of Medical and Dental Sciences, Kagoshima, Japan.
出版信息
Oral Surg Oral Med Oral Pathol Oral Radiol. 2012 Jul;114(1):35-42. doi: 10.1016/j.tripleo.2011.05.028. Epub 2011 Aug 24.
OBJECTIVES
The present study evaluated the effects of bone swaging (BS) with injectable calcium phosphate bone cement (CPC) on periodontal healing in 1-wall intrabony defects in dogs.
STUDY DESIGN
Surgically created 1-wall intrabony defects were treated with BS, CPC, BS with CPC (BS/CPC), or open-flap debridement (OFD). The animals were humanely killed for histologic evaluation at 8 weeks.
RESULTS
New bone formation occurred from the host bone toward the coronal region of the defects in the BS/CPC group. The height of new bone formation was significantly higher in the BS/CPC group than in the other groups (P < .05). New cementum formation was most notable in the BS/CPC group, where it was significantly greater than in the OFD and CPC groups (P < .05).
CONCLUSIONS
Within the limitations of the present study, it was concluded that BS/CPC treatment effectively promoted new bone and cementum formation in 1-wall intrabony defects in dogs.
目的
本研究评估了在骨挤压（BS）联合注射型磷酸钙骨水泥（CPC）治疗犬 1 壁型骨内缺损中的牙周愈合效果。
研究设计
采用手术方法制备 1 壁型骨内缺损，分别采用 BS、CPC、BS 联合 CPC（BS/CPC）或翻瓣清创术（OFD）治疗。在 8 周时，通过人道处死动物进行组织学评估。
结果
BS/CPC 组的新骨从宿主骨向缺损的冠方区域形成。BS/CPC 组的新骨形成高度明显高于其他组（P<.05）。BS/CPC 组的新牙骨质形成最为显著，明显大于 OFD 和 CPC 组（P<.05）。
结论
在本研究的限制范围内，可以得出结论，BS/CPC 治疗可有效促进犬 1 壁型骨内缺损中新骨和牙骨质的形成。
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