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2
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本文引用的文献

1
Isolation and technological properties of coagulase negative staphylococci from fermented sausages of Southern Italy.从意大利南部发酵香肠中分离凝固酶阴性葡萄球菌及其技术特性
Meat Sci. 2004 May;67(1):149-58. doi: 10.1016/j.meatsci.2003.10.003.
2
Acquired antibiotic resistance genes: an overview.获得性抗生素耐药基因：概述。
Front Microbiol. 2011 Sep 28;2:203. doi: 10.3389/fmicb.2011.00203. eCollection 2011.
3
[Antimicrobial resistance of Staphylococcus aureus and coagulase negative staphylococci isolated from mastitis milk samples from sheep and goats].[从绵羊和山羊乳腺炎乳样中分离出的金黄色葡萄球菌和凝固酶阴性葡萄球菌的抗菌耐药性]
Schweiz Arch Tierheilkd. 2011 Feb;153(2):63-9. doi: 10.1024/0036-7281/a000152.
4
Prevalence and characteristics of methicillin-resistant coagulase-negative staphylococci from livestock, chicken carcasses, bulk tank milk, minced meat, and contact persons.耐甲氧西林凝固酶阴性葡萄球菌在牲畜、鸡胴体、散装奶、绞肉和接触者中的流行情况和特征。
BMC Vet Res. 2011 Jan 27;7:6. doi: 10.1186/1746-6148-7-6.
5
Phylogenetic analysis of rRNA methyltransferases, Erm and KsgA, as related to antibiotic resistance.rRNA 甲基转移酶 Erm 和 KsgA 的系统发育分析与抗生素耐药性的关系。
FEMS Microbiol Lett. 2010 Aug 1;309(2):151-62. doi: 10.1111/j.1574-6968.2010.02031.x. Epub 2010 Jun 8.
6
Methicillin-resistant staphylococci isolated from healthy horses and horse personnel in Italy.从意大利健康马匹及养马人员中分离出的耐甲氧西林葡萄球菌。
J Vet Diagn Invest. 2010 Jan;22(1):77-82. doi: 10.1177/104063871002200114.
7
Diversity of staphylococcal cassette chromosome in coagulase-negative staphylococci from animal sources.动物源凝固酶阴性葡萄球菌中葡萄球菌盒式染色体的多样性。
J Appl Microbiol. 2009 Oct;107(4):1375-83. doi: 10.1111/j.1365-2672.2009.04322.x. Epub 2009 Apr 18.
8
A novel gene, erm(41), confers inducible macrolide resistance to clinical isolates of Mycobacterium abscessus but is absent from Mycobacterium chelonae.一种新基因erm(41)可使脓肿分枝杆菌临床分离株产生诱导型大环内酯耐药性，但在龟分枝杆菌中不存在。
Antimicrob Agents Chemother. 2009 Apr;53(4):1367-76. doi: 10.1128/AAC.01275-08. Epub 2009 Jan 26.
9
Antimicrobial susceptibility and distribution of antimicrobial-resistance genes among Enterococcus and coagulase-negative Staphylococcus isolates recovered from poultry litter.从家禽粪便中分离出的肠球菌和凝固酶阴性葡萄球菌的抗菌药敏性及抗菌耐药基因分布情况。
Avian Dis. 2007 Dec;51(4):884-92. doi: 10.1637/7973-032607-REGR.1.
10
Antibiotic resistance patterns of coagulase-negative staphylococcus strains isolated from blood cultures of septicemic patients in Turkey.从土耳其败血症患者血培养中分离出的凝固酶阴性葡萄球菌菌株的抗生素耐药模式。
Microbiol Res. 2009;164(4):404-10. doi: 10.1016/j.micres.2007.03.004. Epub 2007 May 1.

耐林可酰胺类 MLSB 基因 erm(43)在迟缓葡萄球菌中的发现。

New MLSB resistance gene erm(43) in Staphylococcus lentus.

机构信息

Institute of Veterinary Bacteriology, Vetsuisse Faculty, University of Bern, Bern, Switzerland.

出版信息

Antimicrob Agents Chemother. 2012 Sep;56(9):4746-52. doi: 10.1128/AAC.00627-12. Epub 2012 Jun 25.

DOI:10.1128/AAC.00627-12
PMID:22733067
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3421867/
Abstract

The search for a specific rRNA methylase motif led to the identification of the new macrolide, lincosamide, and streptogramin B resistance gene erm(43) in Staphylococcus lentus. An inducible resistance phenotype was demonstrated by cloning and expressing erm(43) and its regulatory region in Staphylococcus aureus. The erm(43) gene was detected in two different DNA fragments, of 6,230 bp and 1,559 bp, that were each integrated at the same location in the chromosome in several S. lentus isolates of human, dog, and chicken origin.

摘要

对特定 rRNA 甲基酶模体的研究导致了新型大环内酯类、林可酰胺类和链阳性菌素 B 耐药基因 erm(43)在葡萄球菌 lentus 中的发现。通过在金黄色葡萄球菌中克隆和表达 erm(43)及其调控区，证明了其具有诱导性耐药表型。在几个人源、犬源和鸡源的葡萄球菌 lentus 分离株中，erm(43)基因被检测到存在于两个不同的 DNA 片段中，分别为 6230bp 和 1559bp，它们都整合在染色体的相同位置上。