Donaldson L J, Cook A, Thomson R G
Northern Regional Health Authority, Walkergate, Newcastle upon Tyne, United Kingdom.
J Epidemiol Community Health. 1990 Sep;44(3):241-5. doi: 10.1136/jech.44.3.241.
The aim was to describe the population based age and sex specific incidence of fractures at different sites in a large English health district.
Recording of fractures was accomplished by a specially constructed outpatient index and by record linkage to hospital inpatient information, for the three years surrounding the 1981 census.
The fracture index was held by the Department of Community Health in Leicester using data from the fracture clinic at the central large district general hospital, supplemented by hospital inpatient data from Trent Region and the two adjoining regions.
The denominator population was the Leicestershire Health Authority resident population. In the three years, 12,711 fractures amongst males and 10,565 amongst females were recorded.
The overall estimated annual incidence of fractures was 100 per 10,000 population for males and 81 per 10,000 population for females. Below the age of 55 years all fractures showed a higher incidence amongst males but amongst the over 55s, there was a consistent fall in the male:female incidence ratio with some sites showing a striking female preponderance. The results also show an apparent age specific temporal increase in incidence at certain fracture sites compared with earlier British data, but fracture incidence figures still suggest lower rates in this country than in North America and some Scandinavian countries.
These findings provide population based incidence data on a major public health problem and are consistent with the major determinants of osteoporosis and increase in falls in postmenopausal women. The temporal and geographical variation in fracture incidence remain to be explained.
旨在描述英国一个大型健康区不同部位骨折基于人群的年龄和性别特异性发病率。
通过一个专门构建的门诊索引以及与医院住院信息的记录链接来记录骨折情况,涵盖1981年人口普查前后三年。
莱斯特社区卫生部持有骨折索引,数据来自中心大型地区综合医院的骨折诊所,并辅以特伦特地区及两个相邻地区的医院住院数据。
分母人群为莱斯特郡卫生局常住人口。在这三年中,记录到男性骨折12711例,女性骨折10565例。
总体估计年骨折发病率男性为每10000人100例,女性为每10000人81例。55岁以下所有骨折男性发病率较高,但55岁以上人群中,男性与女性发病率之比持续下降,某些部位女性占比显著。结果还显示,与英国早期数据相比,某些骨折部位的发病率按年龄呈现明显的时间性上升,但该国的骨折发病率仍低于北美和一些斯堪的纳维亚国家。
这些发现提供了关于一个主要公共卫生问题的基于人群的发病率数据,与骨质疏松症的主要决定因素以及绝经后女性跌倒增加情况相符。骨折发病率的时间和地理差异仍有待解释。