Syzek E J, Bogardus C R
Radiation Therapy Treatment Center, Oklahoma City, OK 73126.
J Okla State Med Assoc. 1990 Nov;83(11):541-5.
Remote afterloading brachytherapy provides effective cancer treatment with zero personnel radiation exposure compared to conventional low dose rate systems requiring inpatient use of iridium, radium, or cesium sources. Clinical use of high dose rate brachytherapy is broadened to encompass curative treatment of cervical, endometrial, endobronchial, head and neck, esophageal, rectal, and prostatic carcinomas as well as palliation of intra-abdominal metastasis intraoperatively. Complications encountered with high dose rate sources will be compared to those of low dose rate systems commonly used in conjunction with external beam irradiation. Radiobiological effectiveness and economic benefits will be addressed to provide support for use of remote afterloading using high dose rate brachytherapy in palliative and curative treatment of selected carcinoma.
与需要住院使用铱、镭或铯源的传统低剂量率系统相比，遥控后装近距离放射疗法可提供有效的癌症治疗，且不会使人员受到辐射。高剂量率近距离放射疗法的临床应用范围得以拓宽，涵盖了宫颈癌、子宫内膜癌、支气管内膜癌、头颈癌、食道癌、直肠癌和前列腺癌的根治性治疗，以及术中对腹腔内转移瘤的姑息治疗。将比较高剂量率源所遇到的并发症与通常与外照射联合使用的低剂量率系统的并发症。还将探讨放射生物学有效性和经济效益，以为在特定癌症的姑息治疗和根治性治疗中使用高剂量率遥控后装近距离放射疗法提供支持。
