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腔内近距离放射治疗食管癌:后装技术的比较

Intraluminal brachytherapy in carcinoma of the oesophagus: comparison of afterloading techniques.

作者信息

Kumar M U, Supe S S, Swamy K, Keshava S L, Anantha N

机构信息

Kidwai Memorial Institute of Oncology, Bangalore, India.

出版信息

Indian J Cancer. 1993 Dec;30(4):181-8.

PMID:7515844
Abstract

For improved local control or palliation of oesophageal cancers, Intra-luminal brachytherapy (ILB) has emerged as an increasingly popular treatment modality of therapy in recent years. In combination with external radiotherapy, afterloaded ILB can increase local control rates and may prolong survival of these patients. In this paper two techniques of ILB viz., manual and low dose-rate remote after loading methods, using Caesium-137 tubes and pellets respectively, are described in detail. On comparison of these two techniques it was found that both of them were similar with respect to their physical characteristics (dose rate, dose fall-off, maximum spinal cord dose, total reference air kerma, etc.). Clinically, the manual afterloaded ILB technique was found to be easier to use when compared with the low-dose rate remote afterloader. In addition, the number of patients with uterine cancers being high in a developing country, it was found that it was inappropriate to use the low dose remote afterloaders, designed for use in gynaecological cancers, for ILB of oesophageal cancers. Therefore, in the absence of high dose rate afterloaders, which can be utilized for intracavitary treatments of both uterine and oesophageal malignancies effectively, the manual after-loading ILB system as described in this paper could be a practical alternative. Cancer Oesophagus, Intraluminal radiotherapy technique.

摘要

为提高食管癌的局部控制率或缓解症状,近年来腔内近距离放疗(ILB)已成为一种越来越受欢迎的治疗方式。与外照射放疗相结合,后装ILB可提高局部控制率,并可能延长这些患者的生存期。本文详细描述了两种ILB技术,即分别使用铯-137管和铯-137粒的手动和低剂量率远程后装方法。比较这两种技术发现,它们在物理特性(剂量率、剂量衰减、脊髓最大剂量、总参考空气比释动能等)方面相似。临床上,与低剂量率远程后装器相比,发现手动后装ILB技术更易于使用。此外,在一个发展中国家,子宫癌患者数量众多,发现将用于妇科癌症的低剂量远程后装器用于食管癌的ILB是不合适的。因此,在缺乏可有效用于子宫和食管恶性肿瘤腔内治疗的高剂量率后装器的情况下,本文所述的手动后装ILB系统可能是一种实用的替代方法。癌症 食管 腔内放疗技术

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