Department of Psychology, Virginia Polytechnic Institute and State University, 109 Williams Hall (0436), Blacksburg, VA 24061, USA.
J Autism Dev Disord. 2013 Feb;43(2):382-94. doi: 10.1007/s10803-012-1577-x.
Anxiety is common among adolescents with autism spectrum disorders (ASD) and may amplify the core social disability, thus necessitating combined treatment approaches. This pilot, randomized controlled trial evaluated the feasibility and preliminary outcomes of the Multimodal Anxiety and Social Skills Intervention (MASSI) program in a sample of 30 adolescents with ASD and anxiety symptoms of moderate or greater severity. The treatment was acceptable to families, subject adherence was high, and therapist fidelity was high. A 16 % improvement in ASD social impairment (within-group effect size = 1.18) was observed on a parent-reported scale. Although anxiety symptoms declined by 26 %, the change was not statistically significant. These findings suggest MASSI is a feasible treatment program and further evaluation is warranted.
焦虑在自闭症谱系障碍（ASD）青少年中很常见，可能会加剧核心社交障碍，因此需要综合治疗方法。本试验性、随机对照试验评估了多模式焦虑和社交技能干预（MASSI）方案在 30 名 ASD 合并中度或更严重焦虑症状的青少年中的可行性和初步结果。该治疗方案得到了家庭的认可，患者的依从性高，治疗师的治疗投入度高。在父母报告的量表上，ASD 社交障碍的改善为 16%（组内效应大小=1.18）。虽然焦虑症状下降了 26%，但变化无统计学意义。这些发现表明 MASSI 是一种可行的治疗方案，值得进一步评估。
