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日本一个社区(久山町)的痴呆症患病率:痴呆症类型的形态学重新评估

Prevalence of dementia in a Japanese community (Hisayama): morphological reappraisal of the type of dementia.

作者信息

Kawano H, Ueda K, Fujishima M

机构信息

Second Department of Internal Medicine, Faculty of Medicine, School of Health Science, Kyushu University, Fukuoka, Japan.

出版信息

Jpn J Med. 1990 May-Jun;29(3):261-5. doi: 10.2169/internalmedicine1962.29.261.

Abstract

The prevalence of dementia was studied in 887 males and females Hisayama residents aged 65 or over (screening rate, 94.6%) using clinical information, neurological examination and dementia scales. We found 59 cases with dementia, the prevalence being in 6.7% of the screened population with females predominant. Vascular dementia was more frequent, with the ratio of vascular dementia to senile dementia of Alzheimer's type being 4.5 for males and 1.2 for females. Brain-pathology in 47 cases with dementia out of 59 was examined by CT scan or at autopsy during the subsequent 20-month period. Based on the morphologic diagnoses, vascular dementia was high in frequency at 55% of the demented cases, being three times higher than senile dementia of Alzheimer's type.

摘要

利用临床信息、神经学检查和痴呆量表,对久山町887名65岁及以上男性和女性居民(筛查率为94.6%)的痴呆患病率进行了研究。我们发现59例痴呆患者,患病率为筛查人群的6.7%,女性居多。血管性痴呆更为常见,男性血管性痴呆与阿尔茨海默型老年痴呆的比例为4.5,女性为1.2。在随后的20个月期间,对59例痴呆患者中的47例进行了脑部CT扫描或尸检。根据形态学诊断,血管性痴呆在痴呆病例中占比高达55%,是阿尔茨海默型老年痴呆的三倍。

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