Yagi S, Hashiguchi K, Nakajima M, Umeki S, Hara H, Soejima R
Department of Medicine, Kawasaki Medical School, Okayama, Japan.
Nihon Kyobu Shikkan Gakkai Zasshi. 1990 Oct;28(10):1366-71.
A 62-year-old female was referred to our division because of general fatigue, low grade fever and exertional dyspnea for 2 months. Laboratory data and chest roentgenograms on admission revealed polycythemia vera associated with idiopathic interstitial pneumonia. Alkylating therapy with carboquone and cyclophosphamide resulted in the improvement of abnormalities on chest X-ray films which had previously shown decreased lung fields and abnormal interstitial shadows, as well as hematological abnormalities. Six months later, the results of the patient's pulmonary function tests and arterial blood gas analysis became within normal limits. Little information about polycythemia vera associated with idiopathic interstitial pneumonia is available. This case indicated that alkylating therapy with no steroidal combination is effective for idiopathic interstitial pneumonia.
一名62岁女性因全身乏力、低热和劳力性呼吸困难2个月转诊至我科。入院时的实验室检查数据和胸部X线片显示真性红细胞增多症合并特发性间质性肺炎。使用卡波醌和环磷酰胺进行烷化剂治疗后，胸部X线片上先前显示肺野减少和间质阴影异常的异常情况以及血液学异常均有所改善。6个月后，患者的肺功能测试和动脉血气分析结果恢复正常。关于真性红细胞增多症合并特发性间质性肺炎的信息很少。该病例表明，非甾体联合烷化剂治疗对特发性间质性肺炎有效。
