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[在患有特发性肺纤维化的免疫功能低下宿主中发生的堪萨斯分枝杆菌肺部感染]

[M. kansasii lung infection occurring in a compromised host with idiopathic pulmonary fibrosis].

作者信息

Umeki S, Tamai H, Okimoto N, Yagi S, Soejima R

出版信息

Kekkaku. 1989 Jul;64(7):479-83.

PMID:2585949
Abstract

A 61-year-old man was admitted to our hospital because of persisting cough, sputum and shortness of breath for four months. Brushing specimens and BALF bronchoscopically obtained revealed acid-fast bacilli and TBLB showed pathological findings consistent with interstitial pneumonia. Based on these results, clinical symptoms, chest roentgenograms on admission and identification of M. kansasii, a diagnosis of M. kansasii lung infection occurred in idiopathic pulmonary fibrosis was made. The patient's symptoms consistent with M. kansasii lung infection and his sputum became negative 6 weeks after antituberculosis chemotherapy with INH, SM and RFP. Because of an increasing dyspnea due to pulmonary fibrosis, however, the patient received oxygen therapy. This case suggested an increasing tendency of compromised hosts associated with M. kansasii lung infection.

摘要

一名61岁男性因持续咳嗽、咳痰和气短4个月入住我院。支气管镜检查获取的刷检标本和支气管肺泡灌洗(BALF)显示抗酸杆菌,经支气管肺活检(TBLB)显示的病理结果符合间质性肺炎。基于这些结果、临床症状、入院时的胸部X线片以及堪萨斯分枝杆菌的鉴定,诊断为特发性肺纤维化合并堪萨斯分枝杆菌肺部感染。该患者符合堪萨斯分枝杆菌肺部感染的症状,在接受异烟肼(INH)、链霉素(SM)和利福平(RFP)抗结核化疗6周后,痰菌转阴。然而,由于肺纤维化导致呼吸困难加重,该患者接受了氧疗。此病例提示与堪萨斯分枝杆菌肺部感染相关的免疫功能低下宿主有增加的趋势。

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