Johns Hopkins Hospital, Baltimore, MD, USA.
Eur J Heart Fail. 2012 Sep;14(9):1041-9. doi: 10.1093/eurjhf/hfs096. Epub 2012 Jun 26.
Mild cognitive impairment (MCI) is prevalent in heart failure, and can contribute to poor self-care and higher hospital readmissions. Strategies to improve self-care in patients with MCI have not been studied. This randomized controlled trial aimed to test the effect of a targeted intervention on self-care, heart failure knowledge, and 30-day readmissions.
The study included 125 patients hospitalized for exacerbation of heart failure who screened positive for MCI. The treatment group received a targeted self-care teaching intervention using principles of cognitive training. Self-care, heart failure knowledge, depression, and social support were assessed at baseline and 30 days post-discharge. Mean heart failure knowledge scores improved significantly in the intervention group, but decreased in the control group (P < 0.001). When controlling for other variables, patients in the intervention group showed a greater increase in heart failure knowledge than patients in the control group (P = 0.027). Black race was significantly associated with lower heart failure knowledge scores (P = 0.030). Mean change scores for self-care showed greater improvement in the intervention group when compared with the control group; however, this was not statistically significant. There was no difference in readmission rates between the groups.
It is feasible to conduct a randomized controlled trial in patients with MCI. Patients in the treatment group had greater heart failure knowledge at 30 days post-discharge; however, this did not impact readmission rates. Further research is needed to describe how MCI affects self-care and knowledge, and how race and other factors may influence outcomes in this population.
轻度认知障碍(MCI)在心力衰竭中较为常见,可导致自我护理不良和住院再入院率升高。尚未研究改善 MCI 患者自我护理的策略。本随机对照试验旨在测试针对自我护理、心力衰竭知识和 30 天再入院率的靶向干预措施的效果。
该研究纳入了 125 名因心力衰竭加重而住院且 MCI 筛查阳性的患者。治疗组接受了基于认知训练原则的靶向自我护理教学干预。在基线和出院后 30 天评估自我护理、心力衰竭知识、抑郁和社会支持。干预组的心力衰竭知识评分显著提高,但对照组则降低(P<0.001)。控制其他变量后,干预组患者的心力衰竭知识增加幅度大于对照组(P=0.027)。黑种人种族与心力衰竭知识评分较低显著相关(P=0.030)。与对照组相比,干预组的自我护理平均变化评分显示出更大的改善,但无统计学意义。两组的再入院率无差异。
在 MCI 患者中开展随机对照试验是可行的。治疗组患者在出院后 30 天的心力衰竭知识更高;但这并未影响再入院率。需要进一步研究描述 MCI 如何影响自我护理和知识,以及种族和其他因素如何影响该人群的结局。