Munoz Javier, Michel Ortega Rosa, Celzo Florence, Donthireddy Vijayalakshmi
Department of Hematology and Oncology, Henry Ford Hospital, Detroit, Michigan, USA.
BMJ Case Rep. 2012 Jun 25;2012:bcr0320125975. doi: 10.1136/bcr.03.2012.5975.
A 60-year-old man presented 2 years before his diagnosis with long-standing muscle cramping, progressive generalised weakness and chronic hip pain. The patient was found to have bilateral femoral neck pathologic fractures therefore, underwent reamed intramedullary nailing of both femurs. Laboratory studies showed hypophosphataemia. Bone marrow biopsy was negative for malignancy. Positron emission tomography demonstrated fludeoxyglucose uptake only in the posterior neck. Bone scan showed innumerable foci of increased activity throughout the skeleton consistent with pseudofractures seen in osteomalacia. Fine needle aspiration from the mass in the neck revealed a phosphaturic mesenchymal tumour of mixed connective tissue type. Resection of the mass in the neck resulted in resolution of generalised complaints with no evidence of recurrence with a follow-up of 12 months.
一名60岁男性在确诊前2年出现长期肌肉痉挛、进行性全身无力和慢性髋部疼痛。该患者被发现双侧股骨颈病理性骨折，因此接受了双侧股骨扩髓髓内钉固定术。实验室检查显示低磷血症。骨髓活检未发现恶性肿瘤。正电子发射断层扫描显示氟脱氧葡萄糖仅在后颈部摄取。骨扫描显示全身有无数活性增加的病灶，与骨软化症中所见的假性骨折一致。颈部肿块的细针穿刺显示为混合结缔组织型的磷尿性间叶肿瘤。切除颈部肿块后，全身症状得到缓解，随访12个月无复发迹象。
