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金修饰碳纤维微电极上半胱氨酸的电化学氧化及其在流通伏安传感器中的应用。

Electrochemical oxidation of cysteine at a film gold modified carbon fiber microelectrode its application in a flow-through voltammetric sensor.

机构信息

Department of Medical Chemistry, Chia Nan University of Pharmacy and Science, Tainan, Taiwan.

出版信息

Sensors (Basel). 2012;12(3):3562-77. doi: 10.3390/s120303562. Epub 2012 Mar 14.

DOI:10.3390/s120303562
PMID:22737024
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3376634/
Abstract

A flow-electrolytical cell containing a strand of micro Au modified carbon fiber electrodes (CFE) has been designedand characterized for use in a voltammatric detector for detecting cysteine using high-performance liquid chromatography. Cysteine is more efficiently electrochemical oxidized on a Au /CFE than a bare gold and carbon fiber electrode. The possible reaction mechanism of the oxidation process is described from the relations to scan rate, peak potentials and currents. For the pulse mode, and measurements with suitable experimental parameters, a linear concentration from 0.5 to 5.0 mg·L(-1) was found. The limit of quantification for cysteine was below 60 ng·mL(-1).

摘要

设计并构建了一种流通式电解池，其中包含一段微 Au 修饰碳纤维电极（CFE），用于高效液相色谱电化学检测胱氨酸。与裸金和碳纤维电极相比，Au/CFE 能更有效地电化学氧化胱氨酸。根据与扫描速率、峰电位和电流的关系，描述了氧化过程的可能反应机制。在脉冲模式下，并采用合适的实验参数进行测量，发现胱氨酸的浓度在 0.5 至 5.0mg·L(-1) 之间呈线性关系。胱氨酸的定量下限低于 60ng·mL(-1)。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/57dc/3376634/1bdb175d1df8/sensors-12-03562f14.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/57dc/3376634/f34fdfbb28c3/sensors-12-03562f9.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/57dc/3376634/5b82230962e7/sensors-12-03562f10.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/57dc/3376634/2dd66944f165/sensors-12-03562f11.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/57dc/3376634/f2dcc1090eea/sensors-12-03562f12.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/57dc/3376634/adb3d2cfa3b8/sensors-12-03562f13.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/57dc/3376634/1bdb175d1df8/sensors-12-03562f14.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/57dc/3376634/c5d67521305a/sensors-12-03562f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/57dc/3376634/d4dd06afb037/sensors-12-03562f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/57dc/3376634/5b0629d846fa/sensors-12-03562f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/57dc/3376634/c55004b02e6f/sensors-12-03562f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/57dc/3376634/be01a18f88b4/sensors-12-03562f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/57dc/3376634/6407ec1da7ef/sensors-12-03562f6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/57dc/3376634/5b88d3e8094f/sensors-12-03562f7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/57dc/3376634/8e969a74e324/sensors-12-03562f8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/57dc/3376634/f34fdfbb28c3/sensors-12-03562f9.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/57dc/3376634/5b82230962e7/sensors-12-03562f10.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/57dc/3376634/2dd66944f165/sensors-12-03562f11.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/57dc/3376634/f2dcc1090eea/sensors-12-03562f12.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/57dc/3376634/adb3d2cfa3b8/sensors-12-03562f13.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/57dc/3376634/1bdb175d1df8/sensors-12-03562f14.jpg

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