短期精子暴露对初产妇先兆子痫发生发展的影响。
The effect of short duration sperm exposure on development of preeclampsia in primigravid women.
作者信息
Sadat Z, Abedzadeh Kalahroudi M, Saberi F
机构信息
Trauma Research Center, School of Nursing and Midwifery, Kashan University of Medical Sciences, Kashan, Iran.
出版信息
Iran Red Crescent Med J. 2012 Jan;14(1):20-4. Epub 2012 Jan 1.
BACKGROUND
Preeclampsia is one of the most serious complications, and affecting about 3% of pregnancies. The aim of this study was to estimate the impact short duration of exposure to sperm on development of preeclampsia.
METHODS
The duration of sperm exposure with the biological father (cohabitation without barrier methods) <3, <6 months were evaluated among 120 primigravid women with preeclampsia and 120 women without preeclampsia in a case-control study.
RESULTS
The short duration of exposure to sperm was more common in women with preeclampsia compared with controls (29.2 versus 14.2 for <3 months, adjOR 2.6 (95% CI=1.32-5.13) and (45 versus 29.2 for <6 months, adjOR 2.4 (95% CI=1.35-4.32). Regardless of the contraceptive method, short duration of cohabitation was more common in preeclamptic group (14.2 versus 5.8 for <3 months, adjOR 3.38 (95% CI=1.28-8.92) and (29.7 versus 13.3 for <6 months, adjOR 2.64(95% CI=1.24-5.79).
CONCLUSION
It was concluded that short duration of exposure to sperm was more common in women with preeclampsia compared with controls.
背景
子痫前期是最严重的并发症之一，影响约3%的妊娠。本研究的目的是评估精子暴露时间短对子痫前期发展的影响。
方法
在一项病例对照研究中，对120例患有子痫前期的初产妇和120例未患子痫前期的妇女，评估其与生物学父亲的精子暴露时间（无屏障方法同居）<3个月、<6个月的情况。
结果
与对照组相比，子痫前期患者精子暴露时间短更为常见（<3个月时为29.2%对14.2%，校正比值比2.6（95%置信区间=1.32 - 5.13）；<6个月时为45%对29.2%，校正比值比2.4（95%置信区间=1.35 - 4.32）。无论采用何种避孕方法，子痫前期组同居时间短更为常见（<3个月时为14.2%对5.8%，校正比值比3.38（95%置信区间=1.28 - 8.92）；<6个月时为29.7%对13.3%，校正比值比2.64（95%置信区间=1.24 - 5.79）。
结论
得出的结论是，与对照组相比，子痫前期患者精子暴露时间短更为常见。
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