Department of Endocrinology, Jinling Hospital, Nanjing University School of Medicine, Nanjing, Jiangsu Province, PR China.
Clin Exp Hypertens. 2012;34(7):474-81. doi: 10.3109/10641963.2012.666601. Epub 2012 Jun 27.
The aim of this study was to assess the prevalence of glucose abnormalities in a Chinese Han population with untreated new-onset hypertension. Four hundred and ninety-nine new-onset hypertensive patients without diabetes were enrolled in this study. An abnormal glucose metabolism was diagnosed in 57.1% of the new-onset hypertensive patients without previously diagnosed diabetes. Stratified by age, the prevalence of diabetes and prediabetes were increased with aging. Male sex, advanced age, higher serum triglycerides, and homeostasis model assessment of insulin resistance levels were all significantly associated with the increased risks of pre-diabetes or diabetes in new-onset hypertensive patients when analyzed by the logistic regression analysis.
本研究旨在评估未经治疗的新发高血压汉人群中葡萄糖异常的流行情况。本研究共纳入 499 例无糖尿病的新发高血压患者。在未经诊断为糖尿病的新发高血压患者中，有 57.1%被诊断为葡萄糖代谢异常。按年龄分层，糖尿病和糖尿病前期的患病率随年龄增长而增加。在逻辑回归分析中，男性、高龄、较高的血清甘油三酯和稳态模型评估的胰岛素抵抗水平均与新发高血压患者发生糖尿病前期或糖尿病的风险增加显著相关。
