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无症状老年合并高血压患者的联合运动训练:对心功能和舒张功能的影响。

Combined exercise training in asymptomatic elderly with controlled hypertension: effects on functional capacity and cardiac diastolic function.

机构信息

Department of Internal Medicine, Botucatu Medical School, Sao Paulo State University, UNESP, SP, Brazil.

出版信息

Med Sci Monit. 2012 Jul;18(7):CR461-5. doi: 10.12659/msm.883215.

DOI:10.12659/msm.883215
PMID:22739737
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3560779/
Abstract

BACKGROUND

Aging is associated with changes in cardiac structure and function that are associated with left ventricular diastolic dysfunction. Whether diastolic functional alterations during senescence are manifestations of the intrinsic aging process or related to cardiac adaptations to a more sedentary lifestyle is still unsettled. This was a prospective study evaluating the effects of a 6-month combined exercise training period on functional capacity and diastolic function in sedentary elderly patients with controlled arterial hypertension.

MATERIAL/METHODS: Functional capacity was assessed by exercise stress test and muscle strength was evaluated by the one-repetition maximum test. Cardiac structures and function were analyzed by transthoracic echocardiography.

RESULTS

Fifteen patients, 68±8 years old, completed the training program. Exercise training significantly improved physical capacity (distance walked: 551±92 vs. 630±153 m, P<0.05; work load: 7.2±1.7 vs. 8.5±3.0 METs, P<0.05) and upper and lower extremity muscle strength (P<0.001). Arterial blood pressure significantly decreased after training (systolic blood pressure: 134±9 vs. 128±8 mmHg; diastolic blood pressure: 82±7 vs. 77±6 mmHg; P<0.05). Cardiac structures and left and right systolic and diastolic function did not change after combined training (P>0.05).

CONCLUSIONS

Combined and supervised training for a 6-month period increases physical capacity and muscle strength in elderly patients with controlled arterial hypertension without changing resting left ventricular diastolic function.

摘要

背景

衰老与心脏结构和功能的变化有关,这些变化与左心室舒张功能障碍有关。在衰老过程中舒张功能的改变是内在衰老过程的表现,还是与心脏适应更久坐不动的生活方式有关,目前仍未确定。这是一项前瞻性研究,评估了 6 个月联合运动训练对控制动脉高血压的久坐老年患者的功能能力和舒张功能的影响。

材料/方法:通过运动应激试验评估功能能力,通过一次最大重复试验评估肌肉力量。通过经胸超声心动图分析心脏结构和功能。

结果

15 名患者,68±8 岁,完成了训练计划。运动训练显著改善了身体能力(步行距离:551±92 与 630±153m,P<0.05;工作量:7.2±1.7 与 8.5±3.0METs,P<0.05)和上下肢肌肉力量(P<0.001)。训练后动脉血压显著降低(收缩压:134±9 与 128±8mmHg;舒张压:82±7 与 77±6mmHg;P<0.05)。联合训练后心脏结构和左、右心室收缩和舒张功能没有变化(P>0.05)。

结论

联合和监督训练 6 个月可增加控制动脉高血压的老年患者的身体能力和肌肉力量,而不会改变静息左心室舒张功能。

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