Bernasovskaia E P, Mel'nitskaia E V, Kondratenko V N
Mikrobiol Zh (1978). 1990 Jul-Aug;52(4):74-9.
Blood-sensitive activity of antigenic extracts obtained from leptospiras using the supersound and sodium dodecyl sulphate has been studied. Erythrocytic diagnostica, obtained on the basis of the mentioned sensitines, possess the genus and serogroup specificity, which expands their diagnostic spectrum. New diagnostica are shown to possess higher sensitivity as compared with the previously developed leptospirosis genus-specific erythrocytic diagnostica. The data are presented confirming the prospects of development of erythrocytic diagnostica based on antigens of leptospiras obtained by means of a supersound and sodium dodecyl sulphate. These preparations may be used in the diagnosis of human and animal leptospirosis.
研究了利用超声波和十二烷基硫酸钠从钩端螺旋体中获得的抗原提取物的血液敏感活性。基于上述致敏原获得的红细胞诊断剂具有属和血清群特异性，这拓宽了它们的诊断范围。结果表明，与先前开发的钩端螺旋体属特异性红细胞诊断剂相比，新型诊断剂具有更高的灵敏度。所提供的数据证实了基于通过超声波和十二烷基硫酸钠获得的钩端螺旋体抗原开发红细胞诊断剂的前景。这些制剂可用于诊断人和动物的钩端螺旋体病。
