通过形成金属环来引发 Csp3-H 键活化：铑（I）催化的炔丙基环丙烷化/环化反应。
C sp 3-H bond activation triggered by formation of metallacycles: rhodium(I)-catalyzed cyclopropanation/cyclization of allenynes.
机构信息
Faculty of Pharmaceutical Sciences, Hokkaido University, Nishi 6, Kita 12, Kita-ku, Sapporo 060-0812, Japan.
出版信息
Angew Chem Int Ed Engl. 2012 Jul 16;51(29):7305-8. doi: 10.1002/anie.201203772. Epub 2012 Jun 27.
PMID:22740384
Abstract
Giving direction: An C sp 3-H bond activation directed by a rhodacycle intermediate has been found to occur in a Rh(I)-catalyzed reaction between an allene moiety having a tert-butyl substituent, and tethered alkynes. Cyclic compounds containing a cyclopropane ring were obtained in good to high yields (up to 92%).
摘要
导向作用
在铑（I）催化的反应中，具有叔丁基取代基的丙二烯部分与连接的炔烃之间，发现通过一个钌环中间体可以使 Csp3-H 键活化。含有环丙烷环的环状化合物以良好至高的收率（高达 92%）获得。
Zotero 插件