Department of Chemistry , Rutgers University , 73 Warren Street , Newark , New Jersey 07102 , United States.
Department of Chemistry and Center for Sustainable Chemistry , Ghent University , Krijgslaan 281 , 9000 Ghent , Belgium.
Chem Rev. 2020 Feb 26;120(4):1981-2048. doi: 10.1021/acs.chemrev.9b00634. Epub 2020 Jan 22.
In this contribution, we provide a comprehensive overview of C-H activation methods promoted by NHC-transition metal complexes, covering the literature since 2002 (the year of the first report on metal-NHC-catalyzed C-H activation) through June 2019, focusing on both NHC ligands and C-H activation methods. This review covers C-H activation reactions catalyzed by group 8 to 11 NHC-metal complexes. Through discussing the role of NHC ligands in promoting challenging C-H activation methods, the reader is provided with an overview of this important area and its crucial role in forging carbon-carbon and carbon-heteroatom bonds by directly engaging ubiquitous C-H bonds.
在本综述中，我们全面概述了 NHC-过渡金属配合物促进的 C-H 键活化方法，涵盖了自 2002 年（首次报道金属-NHC 催化的 C-H 活化的那一年）至 2019 年 6 月的文献，重点关注 NHC 配体和 C-H 键活化方法。本综述涵盖了第 8 族到 11 族 NHC-金属配合物催化的 C-H 键活化反应。通过讨论 NHC 配体在促进具有挑战性的 C-H 键活化方法中的作用，为读者提供了对这一重要领域的概述及其在通过直接利用普遍存在的 C-H 键形成碳-碳和碳-杂原子键方面的关键作用。
