Department of Behavioural Sciences and Learning, Linköping University, Sweden.
PLoS One. 2012;7(5):e38021. doi: 10.1371/journal.pone.0038021. Epub 2012 May 29.
Psychodynamic psychotherapy (PDT) is an effective treatment for major depressive disorder (MDD), but not all clients with MDD can receive psychotherapy. Using the Internet to provide psychodynamic treatments is one way of improving access to psychological treatments for MDD. The aim of this randomised controlled trial was to investigate the efficacy of an Internet-based psychodynamic guided self-help treatment for MDD.
Ninety-two participants who were diagnosed with MDD according to the Mini-International Neuropsychiatric Interview were randomised to treatment or an active control. The treatment consisted of nine treatment modules based on psychodynamic principles with online therapist contact. The active control condition was a structured support intervention and contained psychoeducation and scheduled weekly contacts online. Both interventions lasted for 10 weeks. The primary outcome measure was the Beck Depression Inventory-II (BDI-II).
Mixed-effects model analyses of all randomised participants showed that participants receiving Internet-based PDT made large and superior improvements compared with the active control group on the BDI-II (between-group Cohen's d = 1.11). Treatment effects were maintained at a 10-month follow-up.
Internet-based psychodynamic guided self-help is an efficacious treatment for MDD that has the potential to increase accessibility and availability of PDT for MDD.
Clinicaltrials.gov: NCT01324050.
精神动力学心理治疗(PDT)是治疗重度抑郁症(MDD)的有效方法,但并非所有 MDD 患者都能接受心理治疗。利用互联网提供精神动力学治疗是增加 MDD 心理治疗可及性的一种方法。本随机对照试验旨在探讨基于互联网的精神动力学引导自助治疗 MDD 的疗效。
92 名根据 Mini-International Neuropsychiatric Interview 诊断为 MDD 的参与者被随机分配至治疗组或活性对照组。治疗包括基于精神动力学原理的九个治疗模块,并与在线治疗师进行联系。活性对照组为结构化支持干预,包含心理教育和每周在线预约。两种干预措施均持续 10 周。主要结局测量指标为贝克抑郁量表第二版(BDI-II)。
对所有随机参与者的混合效应模型分析表明,接受基于互联网的 PDT 治疗的患者在 BDI-II 上的改善程度明显优于活性对照组(组间 Cohen's d = 1.11)。治疗效果在 10 个月的随访中得以维持。
基于互联网的精神动力学引导自助治疗是一种治疗 MDD 的有效方法,有可能增加 PDT 治疗 MDD 的可及性和可用性。
Clinicaltrials.gov:NCT01324050。