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阴道前壁脱垂联合修复术后膀胱过度活动症症状改善的预测因素:一项初步研究。

A predictive factor in overactive bladder symptoms improvement after combined anterior vaginal wall prolapse repair: a pilot study.

作者信息

Lee Dong Min, Ryu Young Woo, Lee Yong Taec, Ahn Seung Hyun, Han June Hyun, Yum Seung Hee

机构信息

Department of Urology, KEPCO Medical Foundation, Hanil General Hospital, Seoul, Korea.

出版信息

Korean J Urol. 2012 Jun;53(6):405-9. doi: 10.4111/kju.2012.53.6.405. Epub 2012 Jun 19.

Abstract

PURPOSE

We aimed to determine whether a preoperative urodynamic parameter is a valuable predictor for the persistence of OAB symptoms after the AVP repair.

MATERIALS AND METHODS

65 OAB patients with concomitant POP-Q stage III, IV anterior vaginal wall prolapse underwent a surgical repair were involved. All the patients were subjected to a preoperative urodynamic study, for whom the OABSS on questionnaire were preoperatively recorded. We firstly analyzed the correlation between the BOOI and the OABSS, then randomly divided patients into two groups: the group A (high PdetQmax, BOOI≥20) and the group B (low PdetQmax, BOOI<20). In each group, the OABSS was repeatedly measured post-operatively and the change were analyzed.

RESULTS

31 patients were classified as the group A and 34 patients were classified as the group B. The group B showed significant decrease of symptom score in daytime frequency (p<0.01), urgency (p=0.04), urge incontinence (p=0.03), nocturnal frequency (p=0.01) and total score (p=0.01). The group A showed no significant decrease of symptom score in daytime frequency (p=0.42), urgency (p=0.61), urge incontinence (p=0.3), total score (p=0.15) except nocturnal frequency (p=0.01).

CONCLUSIONS

A preoperative pressure-flow study can be a valuable tool in predicting the OAB symptoms change after the combined AVP repair. While the AVP repair leads to the improvement of OAB symptoms generally, some patients with a higher preoperative PdetQmax are still in need of the additional medical treatment.

摘要

目的

我们旨在确定术前尿动力学参数是否是抗尿失禁吊带(AVP)修复术后膀胱过度活动症(OAB)症状持续存在的有价值预测指标。

材料与方法

纳入65例伴有盆腔器官脱垂定量分期(POP-Q)III期、IV期阴道前壁脱垂的OAB患者,均接受手术修复。所有患者均进行术前尿动力学检查,并在术前通过问卷记录膀胱过度活动症症状评分(OABSS)。我们首先分析膀胱出口梗阻指数(BOOI)与OABSS之间的相关性,然后将患者随机分为两组:A组(最大逼尿肌压力高,BOOI≥20)和B组(最大逼尿肌压力低,BOOI<20)。每组患者术后重复测量OABSS,并分析其变化。

结果

31例患者被归为A组,34例患者被归为B组。B组患者在日间尿频(p<0.01)、尿急(p=0.04)、急迫性尿失禁(p=0.03)夜间尿频(p=0.01)和总分(p=0.01)方面症状评分显著降低。A组患者除夜间尿频(p=0.01)外,在日间尿频(p=0.42)、尿急(p=0.61)、急迫性尿失禁(p=0.3)、总分(p=0.15)方面症状评分无显著降低。

结论

术前压力-流率研究可能是预测联合AVP修复术后OAB症状变化的有价值工具。虽然AVP修复通常会改善OAB症状,但一些术前最大逼尿肌压力较高的患者仍需要额外的药物治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ce9/3382690/25a221bb0473/kju-53-405-g001.jpg

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