Lee Dong Min, Ryu Young Woo, Lee Yong Taec, Ahn Seung Hyun, Han June Hyun, Yum Seung Hee
Department of Urology, KEPCO Medical Foundation, Hanil General Hospital, Seoul, Korea.
Korean J Urol. 2012 Jun;53(6):405-9. doi: 10.4111/kju.2012.53.6.405. Epub 2012 Jun 19.
We aimed to determine whether a preoperative urodynamic parameter is a valuable predictor for the persistence of OAB symptoms after the AVP repair.
65 OAB patients with concomitant POP-Q stage III, IV anterior vaginal wall prolapse underwent a surgical repair were involved. All the patients were subjected to a preoperative urodynamic study, for whom the OABSS on questionnaire were preoperatively recorded. We firstly analyzed the correlation between the BOOI and the OABSS, then randomly divided patients into two groups: the group A (high PdetQmax, BOOI≥20) and the group B (low PdetQmax, BOOI<20). In each group, the OABSS was repeatedly measured post-operatively and the change were analyzed.
31 patients were classified as the group A and 34 patients were classified as the group B. The group B showed significant decrease of symptom score in daytime frequency (p<0.01), urgency (p=0.04), urge incontinence (p=0.03), nocturnal frequency (p=0.01) and total score (p=0.01). The group A showed no significant decrease of symptom score in daytime frequency (p=0.42), urgency (p=0.61), urge incontinence (p=0.3), total score (p=0.15) except nocturnal frequency (p=0.01).
A preoperative pressure-flow study can be a valuable tool in predicting the OAB symptoms change after the combined AVP repair. While the AVP repair leads to the improvement of OAB symptoms generally, some patients with a higher preoperative PdetQmax are still in need of the additional medical treatment.
我们旨在确定术前尿动力学参数是否是抗尿失禁吊带(AVP)修复术后膀胱过度活动症(OAB)症状持续存在的有价值预测指标。
纳入65例伴有盆腔器官脱垂定量分期(POP-Q)III期、IV期阴道前壁脱垂的OAB患者,均接受手术修复。所有患者均进行术前尿动力学检查,并在术前通过问卷记录膀胱过度活动症症状评分(OABSS)。我们首先分析膀胱出口梗阻指数(BOOI)与OABSS之间的相关性,然后将患者随机分为两组:A组(最大逼尿肌压力高,BOOI≥20)和B组(最大逼尿肌压力低,BOOI<20)。每组患者术后重复测量OABSS,并分析其变化。
31例患者被归为A组,34例患者被归为B组。B组患者在日间尿频(p<0.01)、尿急(p=0.04)、急迫性尿失禁(p=0.03)夜间尿频(p=0.01)和总分(p=0.01)方面症状评分显著降低。A组患者除夜间尿频(p=0.01)外,在日间尿频(p=0.42)、尿急(p=0.61)、急迫性尿失禁(p=0.3)、总分(p=0.15)方面症状评分无显著降低。
术前压力-流率研究可能是预测联合AVP修复术后OAB症状变化的有价值工具。虽然AVP修复通常会改善OAB症状,但一些术前最大逼尿肌压力较高的患者仍需要额外的药物治疗。