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经阴道微创网片手术治疗盆腔器官脱垂的短期疗效。

Short-term outcomes of the transvaginal minimal mesh procedure for pelvic organ prolapse.

机构信息

Department of Urology, Juntendo University School of Medicine, Tokyo, Japan.

Department of Urology, Yotsuya Medical Cube, Tokyo, Japan.

出版信息

Investig Clin Urol. 2018 Mar;59(2):133-140. doi: 10.4111/icu.2018.59.2.133. Epub 2018 Feb 2.

DOI:10.4111/icu.2018.59.2.133
PMID:29520390
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5840118/
Abstract

PURPOSE

This study aimed to evaluate the clinical outcomes and complications of transvaginal minimal mesh repair without using commercially available kits for treatment of pelvic organ prolapse (POP).

MATERIALS AND METHODS

This retrospective cohort study involved 91 women who underwent surgical management of POP with originally designed small mesh between July 2014 and August 2015. This mesh is 56% smaller than the mesh widely used in Japan, and it has only two arms delivered into each right and left sacrospinous ligament. The main study outcome was the anatomic cure rate defined as recurrence of POP quantification (POP-Q) stage II or more. We also assessed changes in the overactive bladder symptom score (OABSS) and prolapse quality of life questionnaire (P-QOL) and evaluated adverse events. Finally, we compared patient backgrounds between the patients with and without recurrence.

RESULTS

Prolapse recurred in 10 of 91 patients (11.0%), and all patients with recurrence were diagnosed as POP-Q stage II. As adverse events, only mesh erosion occurred in two (2.2%) and pelvic pain in one (1.1%) of the 91 patients. The OABSS and P-QOL were significantly improved by the operation. When we compared patient backgrounds between the patients with and without recurrence, body mass index was the only factor influencing affecting recurrence.

CONCLUSIONS

Transvaginal minimal mesh repair resulted in successful outcomes with low mesh-related complications and anatomic recurrence at one year. Furthermore, significant improvement in QOL was offered by this procedure. Our minimal mesh technique should be considered as one treatment option for the management of POP.

摘要

目的

本研究旨在评估经阴道应用无市售套件的微创网片修补术治疗盆腔器官脱垂(POP)的临床疗效和并发症。

材料与方法

本回顾性队列研究纳入了 2014 年 7 月至 2015 年 8 月间采用自行设计的小网片治疗 POP 的 91 例女性患者。该网片的面积比日本广泛使用的网片小 56%,仅将两条臂送入左右骶棘韧带。主要研究终点为解剖学治愈率,定义为 POP-Q 分期 II 级或更高级别的复发。我们还评估了膀胱过度活动症症状评分(OABSS)和脱垂生活质量问卷(P-QOL)的变化,并评价了不良事件。最后,我们比较了复发患者和未复发患者的一般情况。

结果

91 例患者中有 10 例(11.0%)复发,所有复发患者均被诊断为 POP-Q 分期 II 级。作为不良事件,91 例患者中仅有 2 例(2.2%)发生网片侵蚀,1 例(1.1%)发生盆腔疼痛。手术可显著改善 OABSS 和 P-QOL。当我们比较复发患者和未复发患者的一般情况时,仅 BMI 是影响复发的唯一因素。

结论

经阴道微创网片修补术可获得良好的效果,且术后一年网片相关并发症和解剖学复发率较低。此外,该手术可显著改善患者的生活质量。我们的微创网片技术应被视为治疗 POP 的一种选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e3c4/5840118/fb86ba5e2f75/icu-59-133-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e3c4/5840118/d9c7c349a84d/icu-59-133-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e3c4/5840118/fb86ba5e2f75/icu-59-133-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e3c4/5840118/d9c7c349a84d/icu-59-133-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e3c4/5840118/fb86ba5e2f75/icu-59-133-g002.jpg

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