New York, N.Y.; and Cleveland, Ohio From Lenox Hill Hospital and Cleveland Clinic.
Plast Reconstr Surg. 2012 Jul;130(1):101-104. doi: 10.1097/PRS.0b013e318254b177.
Although buccal mucosa has been the preferred graft material for use in the reconstruction of anterior urethral strictures for approximately 20 years, the plastic surgery literature is lacking in studies describing and evaluating this technique. The authors sought to report their experience with the technique of buccal mucosa graft harvest for use in urethral reconstruction. The authors identified 87 consecutive patients who underwent buccal mucosal graft harvesting during a 15-year period from 1995 to 2010. All donor sites were closed primarily. Preoperatively, a specialty-specific evaluation was performed by plastic surgeons and urologists. Postoperative donor-site morbidity was followed clinically. Eighty-seven patients underwent buccal harvesting. A single buccal graft was harvested in 75 patients (86.2 percent) and bilateral grafts were harvested in 12 patients (13.8 percent). The median patient age of the patients was 42 years (range, 16 to 78 years). There were no major intraoperative or postoperative complications. Minor complications included mild discomfort, numbness, cheek swelling, and restriction of oral movement, all of which resolved by the 3-month postoperative visit. The ability to eat and drink postoperatively was diminished during only the first 24 to 48 hours in all patients. Our series provides a 1-year follow-up in a substantial cohort looking at clinical outcomes after buccal harvesting. These results confirm the safety and efficacy of buccal mucosal harvesting to provide an effective and cosmetically superior option for urethral reconstruction.
CLINICAL QUESTION/LEVEL OF EVIDENCE: Therapeutic, IV.
尽管颊黏膜作为重建前尿道狭窄的首选移植物已经使用了大约 20 年，但整形外科学文献中缺乏描述和评估该技术的研究。作者旨在报告颊黏膜移植物采集技术在尿道重建中的应用经验。作者确定了 87 例连续患者，他们在 1995 年至 2010 年的 15 年间接受了颊黏膜移植物采集。所有供体部位均采用一期缝合。术前，由整形外科医生和泌尿科医生进行专门的评估。术后随访供体部位的发病率。87 例患者接受颊黏膜采集。75 例患者（86.2%）采集单个颊黏膜移植物，12 例患者（13.8%）采集双侧移植物。患者的中位年龄为 42 岁（范围 16 至 78 岁）。无重大术中或术后并发症。轻微并发症包括轻度不适、麻木、脸颊肿胀和口腔运动受限，所有这些并发症在术后 3 个月随访时均已解决。所有患者仅在术后 24 至 48 小时内短暂出现术后饮食和饮水受限。我们的系列研究提供了一个大规模队列的 1 年随访，观察颊黏膜采集后的临床结果。这些结果证实了颊黏膜采集的安全性和有效性，为尿道重建提供了一种有效且美容效果更好的选择。
临床问题/证据水平：治疗性，IV。
