Trott K R
Zakładu Radiobiologii Uniwersytetu w Londynie.
Nowotwory. 1990 Apr-Jun;40(2):100-4.
The dose which can be given in radiotherapy and, thus, the chance of cancer control is primarily limited by the risk of producing severe chronic side effects in the uninvolved adjacent normal tissues. Only recently the challenge that chronic radiation injury poses to radiobiology has been fully acknowledged and experimental research in laboratory animals has started. Still, very little is known about the pathogenesis, the pathophysiology and the pathology of chronic normal tissue injury of most organs.
放射治疗中能够给予的剂量，进而癌症得到控制的机会，主要受到在未受影响的相邻正常组织中产生严重慢性副作用风险的限制。直到最近，慢性辐射损伤给放射生物学带来的挑战才得到充分认识，并且在实验动物身上的实验研究已经开始。然而，对于大多数器官慢性正常组织损伤的发病机制、病理生理学和病理学仍知之甚少。
