Miller G A
Br Heart J. 1985 Sep;54(3):285-9. doi: 10.1136/hrt.54.3.285.
Balloon dilatation valvuloplasty was performed in 16 patients with pulmonary valve stenosis aged 10 days to 17 years. Gradients were reduced in all but two patients and were less than or equal to 20 mm Hg after the procedure in all but these two and one other. Unsatisfactory initial results in these three patients were attributed to the use of too small a balloon in one patient (gradient subsequently abolished at repeat valvuloplasty), to a dysplastic valve in a neonate, and to the fact that there had been a previous surgical valvotomy with scar tissue formation in one patient. The good result was retained in six of seven patients followed up at three to six months. In one the gradient, having been reduced from 60 to 18 mm Hg, had risen to 35 mm Hg. Repeat valvuloplasty was technically impossible in this patient, but in two others residual gradients of 24 and 22 mm Hg were reduced to 4 and 8 mm Hg respectively by repeat valvuloplasty. Balloon dilatation angioplasty was successful in dilating a severe stenosis at the lower limb of an atrial baffle (previous correction of complete transposition) and in dilating supravalvar stenosis of the pulmonary artery resulting from previous banding and debanding. Thus balloon pulmonary valvuloplasty, though still a new technique, appears to be the treatment of choice in patients with typical pulmonary stenosis and thin mobile valves. Patients with dysplastic valves may be less suitable candidates for the procedure. Balloon angioplasty is likely to have other applications, including the treatment of postoperative stenotic lesions.
对16例年龄在10天至17岁的肺动脉瓣狭窄患者进行了球囊扩张瓣膜成形术。除2例患者外,其余患者的压力阶差均有所降低,除这2例及另外1例患者外,术后所有患者的压力阶差均小于或等于20 mmHg。这3例患者最初结果不理想,其中1例是因为球囊使用过小(在重复瓣膜成形术中压力阶差随后消失),1例是新生儿瓣膜发育不良,另1例是此前曾接受过外科瓣膜切开术并形成了瘢痕组织。在随访3至6个月的7例患者中,6例患者的良好效果得以维持。1例患者的压力阶差从60 mmHg降至18 mmHg后又升至35 mmHg。该患者无法进行重复瓣膜成形术,但另外2例患者通过重复瓣膜成形术,残余压力阶差分别从24 mmHg和22 mmHg降至4 mmHg和8 mmHg。球囊扩张血管成形术成功地扩张了心房挡板下缘的严重狭窄(此前对完全性大动脉转位进行过矫正),以及此前束带和解除束带导致的肺动脉瓣上狭窄。因此,球囊肺动脉瓣膜成形术虽然仍是一项新技术,但似乎是典型肺动脉狭窄且瓣膜薄而可活动患者的首选治疗方法。瓣膜发育不良的患者可能不太适合该手术。球囊血管成形术可能还有其他应用,包括治疗术后狭窄病变。